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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O'Neill LAJ. Runtsch MC, et al. Among authors: fallon pg. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002. Cell Metab. 2022. PMID: 35235776 Free article.
A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins.
Ryan A, Lynch M, Smith SM, Amu S, Nel HJ, McCoy CE, Dowling JK, Draper E, O'Reilly V, McCarthy C, O'Brien J, Ní Eidhin D, O'Connell MJ, Keogh B, Morton CO, Rogers TR, Fallon PG, O'Neill LA, Kelleher D, Loscher CE. Ryan A, et al. Among authors: fallon pg. PLoS Pathog. 2011 Jun;7(6):e1002076. doi: 10.1371/journal.ppat.1002076. Epub 2011 Jun 30. PLoS Pathog. 2011. PMID: 21738466 Free PMC article.
Innate type 2 cells and asthma.
Hams E, Fallon PG. Hams E, et al. Among authors: fallon pg. Curr Opin Pharmacol. 2012 Aug;12(4):503-9. doi: 10.1016/j.coph.2012.06.001. Epub 2012 Jun 29. Curr Opin Pharmacol. 2012. PMID: 22749407 Review.
300 results