Chen J - Search Results

1

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes.

Xu G, Grimes TD, Grayson TB, Chen J, Thielen LA, Tse HM, Li P, Kanke M, Lin TT, Schepmoes AA, Swensen AC, Petyuk VA, Ovalle F, Sethupathy P, Qian WJ, Shalev A. Xu G, et al. Among authors: chen j. Nat Commun. 2022 Mar 3;13(1):1159. doi: 10.1038/s41467-022-28826-3. Nat Commun. 2022. PMID: 35241690 Free PMC article.

2

Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein.

Chen J, Couto FM, Minn AH, Shalev A. Chen J, et al. Biochem Biophys Res Commun. 2006 Aug 4;346(3):1067-74. doi: 10.1016/j.bbrc.2006.06.027. Epub 2006 Jun 13. Biochem Biophys Res Commun. 2006. PMID: 16782054

3

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein.

Chen J, Cha-Molstad H, Szabo A, Shalev A. Chen J, et al. Am J Physiol Endocrinol Metab. 2009 May;296(5):E1133-9. doi: 10.1152/ajpendo.90944.2008. Epub 2009 Mar 3. Am J Physiol Endocrinol Metab. 2009. PMID: 19258488 Free PMC article.

4

Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells.

Cha-Molstad H, Saxena G, Chen J, Shalev A. Cha-Molstad H, et al. Among authors: chen j. J Biol Chem. 2009 Jun 19;284(25):16898-16905. doi: 10.1074/jbc.M109.010504. Epub 2009 May 1. J Biol Chem. 2009. PMID: 19411249 Free PMC article.

5

Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.

Chen J, Fontes G, Saxena G, Poitout V, Shalev A. Chen J, et al. Diabetes. 2010 Feb;59(2):440-7. doi: 10.2337/db09-0949. Epub 2009 Oct 29. Diabetes. 2010. PMID: 19875615 Free PMC article.

6

Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein.

Saxena G, Chen J, Shalev A. Saxena G, et al. Among authors: chen j. J Biol Chem. 2010 Feb 5;285(6):3997-4005. doi: 10.1074/jbc.M109.034421. Epub 2009 Dec 3. J Biol Chem. 2010. PMID: 19959470 Free PMC article.

7

Preventing β-cell loss and diabetes with calcium channel blockers.

Xu G, Chen J, Jing G, Shalev A. Xu G, et al. Among authors: chen j. Diabetes. 2012 Apr;61(4):848-56. doi: 10.2337/db11-0955. Diabetes. 2012. PMID: 22442301 Free PMC article.

8

Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes.

Cha-Molstad H, Xu G, Chen J, Jing G, Young ME, Chatham JC, Shalev A. Cha-Molstad H, et al. Among authors: chen j. Mol Pharmacol. 2012 Sep;82(3):541-9. doi: 10.1124/mol.112.078253. Epub 2012 Jun 25. Mol Pharmacol. 2012. PMID: 22734068 Free PMC article.

9

FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.

Kibbe C, Chen J, Xu G, Jing G, Shalev A. Kibbe C, et al. Among authors: chen j. J Biol Chem. 2013 Aug 9;288(32):23194-202. doi: 10.1074/jbc.M113.473082. Epub 2013 Jun 26. J Biol Chem. 2013. PMID: 23803610 Free PMC article.

10

Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.

Xu G, Chen J, Jing G, Shalev A. Xu G, et al. Among authors: chen j. Nat Med. 2013 Sep;19(9):1141-6. doi: 10.1038/nm.3287. Epub 2013 Aug 25. Nat Med. 2013. PMID: 23975026 Free PMC article.

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