Bratcher PE - Search Results

1

Net benefit of ivacaftor during prolonged tezacaftor/elexacaftor exposure in vitro.

Shaughnessy CA, Zeitlin PL, Bratcher PE. Shaughnessy CA, et al. Among authors: bratcher pe. J Cyst Fibros. 2022 Jul;21(4):637-643. doi: 10.1016/j.jcf.2022.02.011. Epub 2022 Mar 2. J Cyst Fibros. 2022. PMID: 35248469 Free PMC article.

2

Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings.

Bratcher PE, Yadav S, Shaughnessy CA, Thornell IM, Zeitlin PL. Bratcher PE, et al. Physiol Rep. 2020 Oct;8(19):e14603. doi: 10.14814/phy2.14603. Physiol Rep. 2020. PMID: 33038073 Free PMC article.

3

Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation.

Yadav S, Shaughnessy CA, Zeitlin PL, Bratcher PE. Yadav S, et al. Among authors: bratcher pe. BMJ Open Respir Res. 2021 Feb;8(1):e000861. doi: 10.1136/bmjresp-2020-000861. BMJ Open Respir Res. 2021. PMID: 33622672 Free PMC article.

4

Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway.

Shaughnessy CA, Yadav S, Bratcher PE, Zeitlin PL. Shaughnessy CA, et al. Among authors: bratcher pe. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L305-L314. doi: 10.1152/ajplung.00388.2021. Epub 2022 Jan 12. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35020527 Free PMC article.

5

Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment.

Shaughnessy CA, Zeitlin PL, Bratcher PE. Shaughnessy CA, et al. Among authors: bratcher pe. Sci Rep. 2021 Oct 6;11(1):19810. doi: 10.1038/s41598-021-99184-1. Sci Rep. 2021. PMID: 34615919 Free PMC article.

6

Measurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure.

Nick HJ, Zeitlin PL, Yadav S, Bratcher PE. Nick HJ, et al. Among authors: bratcher pe. Sci Rep. 2021 Nov 19;11(1):22616. doi: 10.1038/s41598-021-02044-1. Sci Rep. 2021. PMID: 34799640 Free PMC article.

7

Expanding CFTR Modulator Testing to Carriers of CFTR Variants.

Bratcher PE, Zeitlin PL. Bratcher PE, et al. Ann Am Thorac Soc. 2021 Nov;18(11):1776-1779. doi: 10.1513/AnnalsATS.202011-1397PS. Ann Am Thorac Soc. 2021. PMID: 34133262 No abstract available.

8

Author Correction: Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment.

Shaughnessy CA, Zeitlin PL, Bratcher PE. Shaughnessy CA, et al. Among authors: bratcher pe. Sci Rep. 2021 Oct 25;11(1):21295. doi: 10.1038/s41598-021-00539-5. Sci Rep. 2021. PMID: 34697341 Free PMC article. No abstract available.

9

IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function.

Kotas ME, Moore CM, Gurrola JG 2nd, Pletcher SD, Goldberg AN, Alvarez R, Yamato S, Bratcher PE, Shaughnessy CA, Zeitlin PL, Zhang IH, Li Y, Montgomery MT, Lee K, Cope EK, Locksley RM, Seibold MA, Gordon ED. Kotas ME, et al. Among authors: bratcher pe. JCI Insight. 2022 Jul 8;7(13):e159832. doi: 10.1172/jci.insight.159832. JCI Insight. 2022. PMID: 35608904 Free PMC article.

10

Positive clinical response to ivacaftor treatment in an individual with the CFTR genotype F508del/V456A.

Bratcher PE, Hunt KC, Pickard K, Taylor-Cousar JL. Bratcher PE, et al. J Cyst Fibros. 2019 Mar;18(2):e9-e10. doi: 10.1016/j.jcf.2018.10.008. Epub 2018 Oct 19. J Cyst Fibros. 2019. PMID: 30348612 Free article. No abstract available.

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