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CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.
He L, Arnold C, Thoma J, Rohde C, Kholmatov M, Garg S, Hsiao CC, Viol L, Zhang K, Sun R, Schmidt C, Janssen M, MacRae T, Huber K, Thiede C, Hébert J, Sauvageau G, Spratte J, Fluhr H, Aust G, Müller-Tidow C, Niehrs C, Pereira G, Hamann J, Tanaka M, Zaugg JB, Pabst C. He L, et al. Among authors: hebert j. EMBO Mol Med. 2022 Apr 7;14(4):e14990. doi: 10.15252/emmm.202114990. Epub 2022 Mar 7. EMBO Mol Med. 2022. PMID: 35253392 Free PMC article.
An anticlastogenic function for the Polycomb Group gene Bmi1.
Chagraoui J, Hébert J, Girard S, Sauvageau G. Chagraoui J, et al. Among authors: hebert j. Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5284-9. doi: 10.1073/pnas.1014263108. Epub 2011 Mar 14. Proc Natl Acad Sci U S A. 2011. PMID: 21402923 Free PMC article.
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia.
Simon C, Chagraoui J, Krosl J, Gendron P, Wilhelm B, Lemieux S, Boucher G, Chagnon P, Drouin S, Lambert R, Rondeau C, Bilodeau A, Lavallée S, Sauvageau M, Hébert J, Sauvageau G. Simon C, et al. Among authors: hebert j. Genes Dev. 2012 Apr 1;26(7):651-6. doi: 10.1101/gad.186411.111. Epub 2012 Mar 19. Genes Dev. 2012. PMID: 22431509 Free PMC article.
A role for GPx3 in activity of normal and leukemia stem cells.
Herault O, Hope KJ, Deneault E, Mayotte N, Chagraoui J, Wilhelm BT, Cellot S, Sauvageau M, Andrade-Navarro MA, Hébert J, Sauvageau G. Herault O, et al. Among authors: hebert j. J Exp Med. 2012 May 7;209(5):895-901. doi: 10.1084/jem.20102386. Epub 2012 Apr 16. J Exp Med. 2012. PMID: 22508837 Free PMC article.
1,872 results