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Page 1
Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition.
Schneeweis C, Hassan Z, Ascherl K, Wirth M, Koutsouli S, Orben F, Krauß L, Schneider C, Öllinger R, Krämer OH, Rad R, Reichert M, Robles MS, Saur D, Schneider G. Schneeweis C, et al. Cancer Commun (Lond). 2022 Apr;42(4):360-364. doi: 10.1002/cac2.12280. Epub 2022 Mar 7. Cancer Commun (Lond). 2022. PMID: 35253411 Free PMC article. No abstract available.
MTOR inhibitor-based combination therapies for pancreatic cancer.
Hassan Z, Schneeweis C, Wirth M, Veltkamp C, Dantes Z, Feuerecker B, Ceyhan GO, Knauer SK, Weichert W, Schmid RM, Stauber R, Arlt A, Krämer OH, Rad R, Reichert M, Saur D, Schneider G. Hassan Z, et al. Among authors: schneeweis c. Br J Cancer. 2018 Feb 6;118(3):366-377. doi: 10.1038/bjc.2017.421. Epub 2018 Jan 2. Br J Cancer. 2018. PMID: 29384525 Free PMC article.
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Falcomatà C, Bärthel S, Widholz SA, Schneeweis C, Montero JJ, Toska A, Mir J, Kaltenbacher T, Heetmeyer J, Swietlik JJ, Cheng JY, Teodorescu B, Reichert O, Schmitt C, Grabichler K, Coluccio A, Boniolo F, Veltkamp C, Zukowska M, Vargas AA, Paik WH, Jesinghaus M, Steiger K, Maresch R, Öllinger R, Ammon T, Baranov O, Robles MS, Rechenberger J, Kuster B, Meissner F, Reichert M, Flossdorf M, Rad R, Schmidt-Supprian M, Schneider G, Saur D. Falcomatà C, et al. Among authors: schneeweis c. Nat Cancer. 2022 Mar;3(3):318-336. doi: 10.1038/s43018-021-00326-1. Epub 2022 Jan 31. Nat Cancer. 2022. PMID: 35122074 Free PMC article.
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype.
Biederstädt A, Hassan Z, Schneeweis C, Schick M, Schneider L, Muckenhuber A, Hong Y, Siegers G, Nilsson L, Wirth M, Dantes Z, Steiger K, Schunck K, Langston S, Lenhof HP, Coluccio A, Orben F, Slawska J, Scherger A, Saur D, Müller S, Rad R, Weichert W, Nilsson J, Reichert M, Schneider G, Keller U. Biederstädt A, et al. Among authors: schneeweis c. Gut. 2020 Aug;69(8):1472-1482. doi: 10.1136/gutjnl-2018-317856. Epub 2020 Jan 30. Gut. 2020. PMID: 32001555 Free PMC article.
The SUMO pathway in pancreatic cancer: insights and inhibition.
Schneeweis C, Hassan Z, Schick M, Keller U, Schneider G. Schneeweis C, et al. Br J Cancer. 2021 Feb;124(3):531-538. doi: 10.1038/s41416-020-01119-6. Epub 2020 Oct 19. Br J Cancer. 2021. PMID: 33071285 Free PMC article. Review.
Important role of Nfkb2 in the KrasG12D-driven carcinogenesis in the pancreas.
Hassan Z, Schneeweis C, Wirth M, Müller S, Geismann C, Neuß T, Steiger K, Krämer OH, Schmid RM, Rad R, Arlt A, Reichert M, Saur D, Schneider G. Hassan Z, et al. Among authors: schneeweis c. Pancreatology. 2021 Aug;21(5):912-919. doi: 10.1016/j.pan.2021.03.012. Epub 2021 Mar 26. Pancreatology. 2021. PMID: 33824054 Free article.
A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer.
Lier S, Sellmer A, Orben F, Heinzlmeir S, Krauß L, Schneeweis C, Hassan Z, Schneider C, Patricia Gloria Schäfer A, Pongratz H, Engleitner T, Öllinger R, Kuisl A, Bassermann F, Schlag C, Kong B, Dove S, Kuster B, Rad R, Reichert M, Wirth M, Saur D, Mahboobi S, Schneider G. Lier S, et al. Among authors: schneeweis c. Bioorg Chem. 2022 Feb;119:105505. doi: 10.1016/j.bioorg.2021.105505. Epub 2021 Nov 20. Bioorg Chem. 2022. PMID: 34838332 Free article.
Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype.
Orben F, Lankes K, Schneeweis C, Hassan Z, Jakubowsky H, Krauß L, Boniolo F, Schneider C, Schäfer A, Murr J, Schlag C, Kong B, Öllinger R, Wang C, Beyer G, Mahajan UM, Xue Y, Mayerle J, Schmid RM, Kuster B, Rad R, Braun CJ, Wirth M, Reichert M, Saur D, Schneider G. Orben F, et al. Among authors: schneeweis c. JCI Insight. 2022 May 23;7(10):e151353. doi: 10.1172/jci.insight.151353. JCI Insight. 2022. PMID: 35439169 Free PMC article.
41 results