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1,157 results

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Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation.
Venzon M, Bernard-Raichon L, Klein J, Axelrad JE, Zhang C, Hussey GA, Sullivan AP, Casanovas-Massana A, Noval MG, Valero-Jimenez AM, Gago J, Putzel G, Pironti A, Wilder E; Yale IMPACT Research Team; Thorpe LE, Littman DR, Dittmann M, Stapleford KA, Shopsin B, Torres VJ, Ko AI, Iwasaki A, Cadwell K, Schluter J. Venzon M, et al. Among authors: iwasaki a. bioRxiv [Preprint]. 2022 Mar 2:2021.07.15.452246. doi: 10.1101/2021.07.15.452246. bioRxiv. 2022. Update in: Nat Commun. 2022 Nov 1;13(1):5926. doi: 10.1038/s41467-022-33395-6 PMID: 35262080 Free PMC article. Updated. Preprint.
Coast-to-coast spread of SARS-CoV-2 in the United States revealed by genomic epidemiology.
Fauver JR, Petrone ME, Hodcroft EB, Shioda K, Ehrlich HY, Watts AG, Vogels CBF, Brito AF, Alpert T, Muyombwe A, Razeq J, Downing R, Cheemarla NR, Wyllie AL, Kalinich CC, Ott I, Quick J, Loman NJ, Neugebauer KM, Greninger AL, Jerome KR, Roychoudhury P, Xie H, Shrestha L, Huang ML, Pitzer VE, Iwasaki A, Omer SB, Khan K, Bogoch II, Martinello RA, Foxman EF, Landry ML, Neher RA, Ko AI, Grubaugh ND. Fauver JR, et al. Among authors: iwasaki a. medRxiv [Preprint]. 2020 Mar 26:2020.03.25.20043828. doi: 10.1101/2020.03.25.20043828. medRxiv. 2020. Update in: Cell. 2020 May 28;181(5):990-996.e5. doi: 10.1016/j.cell.2020.04.021 PMID: 32511630 Free PMC article. Updated. Preprint.
SARS-CoV-2 infection of the placenta.
Hosier H, Farhadian SF, Morotti RA, Deshmukh U, Lu-Culligan A, Campbell KH, Yasumoto Y, Vogels CB, Casanovas-Massana A, Vijayakumar P, Geng B, Odio CD, Fournier J, Brito AF, Fauver JR, Liu F, Alpert T, Tal R, Szigeti-Buck K, Perincheri S, Larsen C, Gariepy AM, Aguilar G, Fardelmann KL, Harigopal M, Taylor HS, Pettker CM, Wyllie AL, Cruz CD, Ring AM, Grubaugh ND, Ko AI, Horvath TL, Iwasaki A, Reddy UM, Lipkind HS. Hosier H, et al. Among authors: iwasaki a. J Clin Invest. 2020 Sep 1;130(9):4947-4953. doi: 10.1172/JCI139569. J Clin Invest. 2020. PMID: 32573498 Free PMC article.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Israelow B, et al. Among authors: iwasaki a. bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. Update in: J Exp Med. 2020 Dec 7;217(12):e20201241. doi: 10.1084/jem.20201241 PMID: 32577647 Free PMC article. Updated. Preprint.
Sex differences in immune responses to SARS-CoV-2 that underlie disease outcomes.
Takahashi T, Wong P, Ellingson MK, Lucas C, Klein J, Israelow B, Silva J, Oh JE, Mao T, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Casanovas-Massana A, Cruz CD, Fournier JB, Odio CD, Farhadian S, Grubaugh ND, Schulz WL, Ko AI, Ring AM, Omer SB, Iwasaki A; Yale IMPACT research team. Takahashi T, et al. Among authors: iwasaki a. medRxiv [Preprint]. 2020 Jun 26:2020.06.06.20123414. doi: 10.1101/2020.06.06.20123414. medRxiv. 2020. Update in: Nature. 2020 Dec;588(7837):315-320. doi: 10.1038/s41586-020-2700-3 PMID: 32577695 Free PMC article. Updated. Preprint.
Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT-qPCR primer-probe sets.
Vogels CBF, Brito AF, Wyllie AL, Fauver JR, Ott IM, Kalinich CC, Petrone ME, Casanovas-Massana A, Catherine Muenker M, Moore AJ, Klein J, Lu P, Lu-Culligan A, Jiang X, Kim DJ, Kudo E, Mao T, Moriyama M, Oh JE, Park A, Silva J, Song E, Takahashi T, Taura M, Tokuyama M, Venkataraman A, Weizman OE, Wong P, Yang Y, Cheemarla NR, White EB, Lapidus S, Earnest R, Geng B, Vijayakumar P, Odio C, Fournier J, Bermejo S, Farhadian S, Dela Cruz CS, Iwasaki A, Ko AI, Landry ML, Foxman EF, Grubaugh ND. Vogels CBF, et al. Among authors: iwasaki a. Nat Microbiol. 2020 Oct;5(10):1299-1305. doi: 10.1038/s41564-020-0761-6. Epub 2020 Jul 10. Nat Microbiol. 2020. PMID: 32651556 Free PMC article.
Longitudinal analyses reveal immunological misfiring in severe COVID-19.
Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, Mohanty S, Wang H, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Muenker MC, Fournier JB, Campbell M, Odio CD, Casanovas-Massana A; Yale IMPACT Team; Herbst R, Shaw AC, Medzhitov R, Schulz WL, Grubaugh ND, Dela Cruz C, Farhadian S, Ko AI, Omer SB, Iwasaki A. Lucas C, et al. Among authors: iwasaki a. Nature. 2020 Aug;584(7821):463-469. doi: 10.1038/s41586-020-2588-y. Epub 2020 Jul 27. Nature. 2020. PMID: 32717743 Free PMC article.
Clinical Characteristics and Outcomes for 7,995 Patients with SARS-CoV-2 Infection.
McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJ, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Cruz CSD, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ Jr, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. McPadden J, et al. Among authors: iwasaki a. medRxiv [Preprint]. 2020 Nov 8:2020.07.19.20157305. doi: 10.1101/2020.07.19.20157305. medRxiv. 2020. Update in: PLoS One. 2021 Mar 31;16(3):e0243291. doi: 10.1371/journal.pone.0243291 PMID: 32743602 Free PMC article. Updated. Preprint.
Simply saliva: stability of SARS-CoV-2 detection negates the need for expensive collection devices.
Ott IM, Strine MS, Watkins AE, Boot M, Kalinich CC, Harden CA, Vogels CBF, Casanovas-Massana A, Moore AJ, Muenker MC, Nakahata M, Tokuyama M, Nelson A, Fournier J, Bermejo S, Campbell M, Datta R; Yale IMPACT Research team; Dela Cruz CS, Farhadian SF, Ko AI, Iwasaki A, Grubaugh ND, Wilen CB, Wyllie AL. Ott IM, et al. Among authors: iwasaki a. medRxiv [Preprint]. 2020 Aug 4:2020.08.03.20165233. doi: 10.1101/2020.08.03.20165233. medRxiv. 2020. Update in: Emerg Infect Dis. 2021 Apr;27(4):1146-1150. doi: 10.3201/eid2704.204199 PMID: 32793924 Free PMC article. Updated. Preprint.
Sex differences in immune responses that underlie COVID-19 disease outcomes.
Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Casanovas-Massana A, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ; Yale IMPACT Research Team; Shaw A, Fournier JB, Odio CD, Farhadian S, Dela Cruz C, Grubaugh ND, Schulz WL, Ring AM, Ko AI, Omer SB, Iwasaki A. Takahashi T, et al. Among authors: iwasaki a. Nature. 2020 Dec;588(7837):315-320. doi: 10.1038/s41586-020-2700-3. Epub 2020 Aug 26. Nature. 2020. PMID: 32846427 Free PMC article.
1,157 results