Lio D - Search Results

1

Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation.

Robin AY, Miller MS, Iyer S, Shi MX, Wardak AZ, Lio D, Smith NA, Smith BJ, Birkinshaw RW, Czabotar PE, Kluck RM, Colman PM. Robin AY, et al. Among authors: lio d. Cell Death Differ. 2022 Sep;29(9):1757-1768. doi: 10.1038/s41418-022-00961-w. Epub 2022 Mar 12. Cell Death Differ. 2022. PMID: 35279694 Free PMC article.

2

Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.

Birkinshaw RW, Gong JN, Luo CS, Lio D, White CA, Anderson MA, Blombery P, Lessene G, Majewski IJ, Thijssen R, Roberts AW, Huang DCS, Colman PM, Czabotar PE. Birkinshaw RW, et al. Among authors: lio d. Nat Commun. 2019 Jun 3;10(1):2385. doi: 10.1038/s41467-019-10363-1. Nat Commun. 2019. PMID: 31160589 Free PMC article.

3

Structure of detergent-activated BAK dimers derived from the inert monomer.

Birkinshaw RW, Iyer S, Lio D, Luo CS, Brouwer JM, Miller MS, Robin AY, Uren RT, Dewson G, Kluck RM, Colman PM, Czabotar PE. Birkinshaw RW, et al. Among authors: lio d. Mol Cell. 2021 May 20;81(10):2123-2134.e5. doi: 10.1016/j.molcel.2021.03.014. Epub 2021 Mar 31. Mol Cell. 2021. PMID: 33794146 Free article.

4

Dynamic reconfiguration of pro-apoptotic BAK on membranes.

Sandow JJ, Tan IK, Huang AS, Masaldan S, Bernardini JP, Wardak AZ, Birkinshaw RW, Ninnis RL, Liu Z, Dalseno D, Lio D, Infusini G, Czabotar PE, Webb AI, Dewson G. Sandow JJ, et al. Among authors: lio d. EMBO J. 2021 Oct 18;40(20):e107237. doi: 10.15252/embj.2020107237. Epub 2021 Sep 15. EMBO J. 2021. PMID: 34523147 Free PMC article.

5

A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells.

Subas Satish HP, Iyer S, Shi MX, Wong AW, Fischer KC, Wardak AZ, Lio D, Brouwer JM, Uren RT, Czabotar PE, Miller MS, Kluck RM. Subas Satish HP, et al. Among authors: lio d. Cell Death Differ. 2024 Jun;31(6):711-721. doi: 10.1038/s41418-024-01289-3. Epub 2024 Apr 6. Cell Death Differ. 2024. PMID: 38582955 Free PMC article.

6

The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement.

Metcalfe RD, Aizel K, Zlatic CO, Nguyen PM, Morton CJ, Lio DS, Cheng HC, Dobson RCJ, Parker MW, Gooley PR, Putoczki TL, Griffin MDW. Metcalfe RD, et al. Among authors: lio ds. J Biol Chem. 2020 Jun 12;295(24):8285-8301. doi: 10.1074/jbc.RA119.012351. Epub 2020 Apr 24. J Biol Chem. 2020. PMID: 32332100 Free PMC article.

7

Development of the procedures for high-yield expression and rapid purification of active recombinant Csk-homologous kinase (CHK): comparison of the catalytic activities of CHK and CSK.

Chan KC, Lio DS, Dobson RC, Jarasrassamee B, Hossain MI, Roslee AK, Ia KK, Perugini MA, Cheng HC. Chan KC, et al. Protein Expr Purif. 2010 Dec;74(2):139-47. doi: 10.1016/j.pep.2010.07.007. Epub 2010 Jul 25. Protein Expr Purif. 2010. PMID: 20667476

8

Activation of Src family tyrosine kinases by ferric ions.

Baldwin GS, Lio DS, Ferrand A, Catimel B, Shehan BP, Norton RS, Cheng HC. Baldwin GS, et al. Biochim Biophys Acta. 2014 Mar;1844(3):487-96. doi: 10.1016/j.bbapap.2013.12.004. Epub 2013 Dec 12. Biochim Biophys Acta. 2014. PMID: 24334106 Free article.

9

The Roc-COR tandem domain of leucine-rich repeat kinase 2 forms dimers and exhibits conventional Ras-like GTPase properties.

Mills RD, Liang LY, Lio DS, Mok YF, Mulhern TD, Cao G, Griffin M, Kenche VB, Culvenor JG, Cheng HC. Mills RD, et al. Among authors: lio ds. J Neurochem. 2018 Nov;147(3):409-428. doi: 10.1111/jnc.14566. J Neurochem. 2018. PMID: 30091236 Free article.

10

Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide.

Ngoei KR, Catimel B, Church N, Lio DS, Dogovski C, Perugini MA, Watt PM, Cheng HC, Ng DC, Bogoyevitch MA. Ngoei KR, et al. Biochem J. 2011 Mar 15;434(3):399-413. doi: 10.1042/BJ20101244. Biochem J. 2011. PMID: 21162712

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