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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses.
Mittler E, Wec AZ, Tynell J, Guardado-Calvo P, Wigren-Byström J, Polanco LC, O'Brien CM, Slough MM, Abelson DM, Serris A, Sakharkar M, Pehau-Arnaudet G, Bakken RR, Geoghegan JC, Jangra RK, Keller M, Zeitlin L, Vapalahti O, Ulrich RG, Bornholdt ZA, Ahlm C, Rey FA, Dye JM, Bradfute SB, Strandin T, Herbert AS, Forsell MNE, Walker LM, Chandran K. Mittler E, et al. Sci Transl Med. 2022 Mar 16;14(636):eabl5399. doi: 10.1126/scitranslmed.abl5399. Epub 2022 Mar 16. Sci Transl Med. 2022. PMID: 35294259 Free PMC article.
Recognition determinants of broadly neutralizing human antibodies against dengue viruses.
Rouvinski A, Guardado-Calvo P, Barba-Spaeth G, Duquerroy S, Vaney MC, Kikuti CM, Navarro Sanchez ME, Dejnirattisai W, Wongwiwat W, Haouz A, Girard-Blanc C, Petres S, Shepard WE, Desprès P, Arenzana-Seisdedos F, Dussart P, Mongkolsapaya J, Screaton GR, Rey FA. Rouvinski A, et al. Nature. 2015 Apr 2;520(7545):109-13. doi: 10.1038/nature14130. Epub 2015 Jan 12. Nature. 2015. PMID: 25581790 Free article.
Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.
Guardado-Calvo P, Bignon EA, Stettner E, Jeffers SA, Pérez-Vargas J, Pehau-Arnaudet G, Tortorici MA, Jestin JL, England P, Tischler ND, Rey FA. Guardado-Calvo P, et al. PLoS Pathog. 2016 Oct 26;12(10):e1005813. doi: 10.1371/journal.ppat.1005813. eCollection 2016 Oct. PLoS Pathog. 2016. PMID: 27783711 Free PMC article.
The Envelope Proteins of the Bunyavirales.
Guardado-Calvo P, Rey FA. Guardado-Calvo P, et al. Adv Virus Res. 2017;98:83-118. doi: 10.1016/bs.aivir.2017.02.002. Epub 2017 Apr 8. Adv Virus Res. 2017. PMID: 28433053 Review.
Structure-Function Dissection of Pseudorabies Virus Glycoprotein B Fusion Loops.
Vallbracht M, Brun D, Tassinari M, Vaney MC, Pehau-Arnaudet G, Guardado-Calvo P, Haouz A, Klupp BG, Mettenleiter TC, Rey FA, Backovic M. Vallbracht M, et al. J Virol. 2017 Dec 14;92(1):e01203-17. doi: 10.1128/JVI.01203-17. Print 2018 Jan 1. J Virol. 2017. PMID: 29046441 Free PMC article.
Protocadherin-1 is essential for cell entry by New World hantaviruses.
Jangra RK, Herbert AS, Li R, Jae LT, Kleinfelter LM, Slough MM, Barker SL, Guardado-Calvo P, Román-Sosa G, Dieterle ME, Kuehne AI, Muena NA, Wirchnianski AS, Nyakatura EK, Fels JM, Ng M, Mittler E, Pan J, Bharrhan S, Wec AZ, Lai JR, Sidhu SS, Tischler ND, Rey FA, Moffat J, Brummelkamp TR, Wang Z, Dye JM, Chandran K. Jangra RK, et al. Nature. 2018 Nov;563(7732):559-563. doi: 10.1038/s41586-018-0702-1. Epub 2018 Nov 21. Nature. 2018. PMID: 30464266 Free PMC article.
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