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Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency.
Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA. Telwatte S, et al. Among authors: lee s. PLoS Pathog. 2018 Nov 15;14(11):e1007357. doi: 10.1371/journal.ppat.1007357. eCollection 2018 Nov. PLoS Pathog. 2018. PMID: 30440043 Free PMC article.
Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay.
Lee SA, Telwatte S, Hatano H, Kashuba ADM, Cottrell ML, Hoh R, Liegler TJ, Stephenson S, Somsouk M, Hunt PW, Deeks SG, Yukl S, Savic RM. Lee SA, et al. J Acquir Immune Defic Syndr. 2020 Apr 15;83(5):530-537. doi: 10.1097/QAI.0000000000002287. J Acquir Immune Defic Syndr. 2020. PMID: 32168200 Free PMC article.
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. Hsiao F, et al. Among authors: lee gq, lee s. PLoS Pathog. 2020 Apr 30;16(4):e1008450. doi: 10.1371/journal.ppat.1008450. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32353080 Free PMC article.
SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential.
Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George A, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. Neidleman J, et al. bioRxiv [Preprint]. 2020 Aug 3:2020.06.08.138826. doi: 10.1101/2020.06.08.138826. bioRxiv. 2020. Update in: Cell Rep Med. 2020 Sep 22;1(6):100081. doi: 10.1016/j.xcrm.2020.100081 PMID: 32577663 Free PMC article. Updated. Preprint.
Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19.
Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR. Neidleman J, et al. medRxiv [Preprint]. 2021 Feb 5:2021.01.22.21250054. doi: 10.1101/2021.01.22.21250054. medRxiv. 2021. Update in: Cell Rep. 2021 Jul 20;36(3):109414. doi: 10.1016/j.celrep.2021.109414 PMID: 33532792 Free PMC article. Updated. Preprint.
2,034 results