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Page 1
Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.
Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, Alhayyani S, Tate MD, Deswaerte V, Brooks GD, Bozinovski S, MacDonald M, Garbers C, King PT, Bardin PG, Vlahos R, Rose-John S, Anderson GP, Jenkins BJ. Ruwanpura SM, et al. Among authors: deswaerte v. Am J Respir Crit Care Med. 2016 Dec 15;194(12):1494-1505. doi: 10.1164/rccm.201512-2368OC. Am J Respir Crit Care Med. 2016. PMID: 27373892
Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.
Deswaerte V, Nguyen P, West A, Browning AF, Yu L, Ruwanpura SM, Balic J, Livis T, Girard C, Preaudet A, Oshima H, Fung KY, Tye H, Najdovska M, Ernst M, Oshima M, Gabay C, Putoczki T, Jenkins BJ. Deswaerte V, et al. Cancer Res. 2018 Mar 1;78(5):1293-1307. doi: 10.1158/0008-5472.CAN-17-1887. Epub 2017 Dec 27. Cancer Res. 2018. PMID: 29282220
Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells.
Tafreshi M, Guan J, Gorrell RJ, Chew N, Xin Y, Deswaerte V, Rohde M, Daly RJ, Peek RM Jr, Jenkins BJ, Davies EM, Kwok T. Tafreshi M, et al. Among authors: deswaerte v. Front Cell Infect Microbiol. 2018 Feb 6;8:22. doi: 10.3389/fcimb.2018.00022. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 29468142 Free PMC article.
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Saad MI, Alhayyani S, McLeod L, Yu L, Alanazi M, Deswaerte V, Tang K, Jarde T, Smith JA, Prodanovic Z, Tate MD, Balic JJ, Watkins DN, Cain JE, Bozinovski S, Algar E, Kohmoto T, Ebi H, Ferlin W, Garbers C, Ruwanpura S, Sagi I, Rose-John S, Jenkins BJ. Saad MI, et al. Among authors: deswaerte v. EMBO Mol Med. 2019 Apr;11(4):e9976. doi: 10.15252/emmm.201809976. EMBO Mol Med. 2019. PMID: 30833304 Free PMC article.
Constitutive STAT3 Serine Phosphorylation Promotes Helicobacter-Mediated Gastric Disease.
Balic JJ, Saad MI, Dawson R, West AJ, McLeod L, West AC, D'Costa K, Deswaerte V, Dev A, Sievert W, Gough DJ, Bhathal PS, Ferrero RL, Jenkins BJ. Balic JJ, et al. Among authors: deswaerte v. Am J Pathol. 2020 Jun;190(6):1256-1270. doi: 10.1016/j.ajpath.2020.01.021. Epub 2020 Mar 19. Am J Pathol. 2020. PMID: 32201262 Free article.
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.
Dawson RE, Deswaerte V, West AC, Tang K, West AJ, Balic JJ, Gearing LJ, Saad MI, Yu L, Wu Y, Bhathal PS, Kumar B, Chakrabarti JT, Zavros Y, Oshima H, Klinman DM, Oshima M, Tan P, Jenkins BJ. Dawson RE, et al. Among authors: deswaerte v. Gut. 2022 Aug;71(8):1515-1531. doi: 10.1136/gutjnl-2020-323916. Epub 2021 Sep 6. Gut. 2022. PMID: 34489308
21 results