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Computed tomography and [18F]-FDG PET imaging provide additional readouts for COVID-19 pathogenesis and therapies evaluation in non-human primates.
Naninck T, Kahlaoui N, Lemaitre J, Maisonnasse P, De Mori A, Pascal Q, Contreras V, Marlin R, Relouzat F, Delache B, Hérate C, Aldon Y, van Gils M, Zabaleta N, Ho Tsong Fang R, Bosquet N, Sanders RW, Vandenberghe LH, Chapon C, Le Grand R. Naninck T, et al. Among authors: vandenberghe lh. iScience. 2022 Apr 15;25(4):104101. doi: 10.1016/j.isci.2022.104101. Epub 2022 Mar 17. iScience. 2022. PMID: 35313622 Free PMC article.
GPR108 Is a Highly Conserved AAV Entry Factor.
Dudek AM, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, Franceschini JS, Estelien R, Carette JE, Zhou GL, Vandenberghe LH. Dudek AM, et al. Among authors: vandenberghe lh. Mol Ther. 2020 Feb 5;28(2):367-381. doi: 10.1016/j.ymthe.2019.11.005. Epub 2019 Nov 13. Mol Ther. 2020. PMID: 31784416 Free PMC article.
An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Naninck T, Kahlaoui N, Lemaitre J, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Contreras V, Marlin R, Tsong Fang RH, Chapon C, van der Werf S, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Le Grand R, Vandenberghe LH. Zabaleta N, et al. Among authors: vandenberghe lh. Cell Host Microbe. 2021 Sep 8;29(9):1437-1453.e8. doi: 10.1016/j.chom.2021.08.002. Epub 2021 Aug 7. Cell Host Microbe. 2021. PMID: 34428428 Free PMC article.
Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques.
Zabaleta N, Bhatt U, Hérate C, Maisonnasse P, Sanmiguel J, Diop C, Castore S, Estelien R, Li D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Pascal Q, Naninck T, Kahlaoui N, Lemaitre J, Relouzat F, Ronzitti G, Thibaut HJ, Montomoli E, Wilson JM, Le Grand R, Vandenberghe LH. Zabaleta N, et al. Among authors: vandenberghe lh. Mol Ther. 2022 Sep 7;30(9):2952-2967. doi: 10.1016/j.ymthe.2022.05.007. Epub 2022 May 10. Mol Ther. 2022. PMID: 35546782 Free PMC article.
Ancestral library identifies conserved reprogrammable liver motif on AAV capsid.
Zinn E, Unzu C, Schmit PF, Turunen HT, Zabaleta N, Sanmiguel J, Fieldsend A, Bhatt U, Diop C, Merkel E, Gurrala R, Peacker B, Rios C, Messemer K, Santos J, Estelien R, Andres-Mateos E, Wagers AJ, Tipper C, Vandenberghe LH. Zinn E, et al. Among authors: vandenberghe lh. Cell Rep Med. 2022 Nov 15;3(11):100803. doi: 10.1016/j.xcrm.2022.100803. Epub 2022 Nov 2. Cell Rep Med. 2022. PMID: 36327973 Free PMC article.
Boost and Increased Antibody Breadth Following a Second Dose of PARVAX for SARS-CoV-2 in Mice and Nonhuman Primates.
Bhatt U, Herate C, Estelien R, Relouzat F, Dereuddre-Bosquet N, Maciorowski D, Diop C, Couto E, Staiti J, Cavarelli M, Bossevot L, Sconosciuti Q, Bouchard P, Le Grand R, Vandenberghe LH, Zabaleta N. Bhatt U, et al. Among authors: vandenberghe lh. Vaccines (Basel). 2024 Aug 2;12(8):882. doi: 10.3390/vaccines12080882. Vaccines (Basel). 2024. PMID: 39204008 Free PMC article.
Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates.
Zabaleta N, Dai W, Bhatt U, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Vandenberghe LH. Zabaleta N, et al. Among authors: vandenberghe lh. bioRxiv [Preprint]. 2021 Jan 19:2021.01.05.422952. doi: 10.1101/2021.01.05.422952. bioRxiv. 2021. Update in: Cell Host Microbe. 2021 Sep 8;29(9):1437-1453.e8. doi: 10.1016/j.chom.2021.08.002. PMID: 33442684 Free PMC article. Updated. Preprint.
COVID-19: Gene Transfer to the Rescue?
Vandenberghe LH. Vandenberghe LH. Hum Gene Ther. 2020 Jun;31(11-12):605-607. doi: 10.1089/hum.2020.29125.lhv. Epub 2020 May 28. Hum Gene Ther. 2020. PMID: 32469280 No abstract available.
111 results