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Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.
McElroy GS, Chakrabarty RP, D'Alessandro KB, Hu YS, Vasan K, Tan J, Stoolman JS, Weinberg SE, Steinert EM, Reyfman PA, Singer BD, Ladiges WC, Gao L, Lopéz-Barneo J, Ridge K, Budinger GRS, Chandel NS. McElroy GS, et al. Among authors: singer bd. Sci Rep. 2022 Mar 25;12(1):5196. doi: 10.1038/s41598-022-09074-3. Sci Rep. 2022. PMID: 35338200 Free PMC article.
Transcriptomic signatures decode Th17 cell pathogenicity.
Reyfman PA, Bartom ET, Singer BD. Reyfman PA, et al. Among authors: singer bd. Cell Mol Immunol. 2016 Sep;13(5):557-9. doi: 10.1038/cmi.2016.22. Epub 2016 May 2. Cell Mol Immunol. 2016. PMID: 27133470 Free PMC article. No abstract available.
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.
Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H. Misharin AV, et al. Among authors: singer bd. J Exp Med. 2017 Aug 7;214(8):2387-2404. doi: 10.1084/jem.20162152. Epub 2017 Jul 10. J Exp Med. 2017. PMID: 28694385 Free PMC article.
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.
Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, Gonzalez-Gonzalez FJ, Soberanes S, Watanabe S, Williams KJN, Flozak AS, Nicholson TT, Morgan VK, Winter DR, Hinchcliff M, Hrusch CL, Guzy RD, Bonham CA, Sperling AI, Bag R, Hamanaka RB, Mutlu GM, Yeldandi AV, Marshall SA, Shilatifard A, Amaral LAN, Perlman H, Sznajder JI, Argento AC, Gillespie CT, Dematte J, Jain M, Singer BD, Ridge KM, Lam AP, Bharat A, Bhorade SM, Gottardi CJ, Budinger GRS, Misharin AV. Reyfman PA, et al. Among authors: singer bd. Am J Respir Crit Care Med. 2019 Jun 15;199(12):1517-1536. doi: 10.1164/rccm.201712-2410OC. Am J Respir Crit Care Med. 2019. PMID: 30554520 Free PMC article.
A Call for Rational Intensive Care in the Era of COVID-19.
Singer BD, Jain M, Budinger GRS, Wunderink RG. Singer BD, et al. Am J Respir Cell Mol Biol. 2020 Jul;63(1):132-133. doi: 10.1165/rcmb.2020-0151LE. Am J Respir Cell Mol Biol. 2020. PMID: 32315548 Free PMC article. No abstract available.
Age-Dependent Differences in T-Cell Responses to Influenza A Virus.
Prigge AD, Ma R, Coates BM, Singer BD, Ridge KM. Prigge AD, et al. Among authors: singer bd. Am J Respir Cell Mol Biol. 2020 Oct;63(4):415-423. doi: 10.1165/rcmb.2020-0169TR. Am J Respir Cell Mol Biol. 2020. PMID: 32609537 Free PMC article. Review.
Comparing Nasopharyngeal and BAL SARS-CoV-2 Assays in Respiratory Failure.
Gao CA, Cuttica MJ, Malsin ES, Argento AC, Wunderink RG, Smith SB; NU COVID Investigators. Gao CA, et al. Am J Respir Crit Care Med. 2021 Jan 1;203(1):127-129. doi: 10.1164/rccm.202008-3137LE. Am J Respir Crit Care Med. 2021. PMID: 33125256 Free PMC article. No abstract available.
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Among authors: singer bd. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. McQuattie-Pimentel AC, et al. Among authors: singer bd. J Clin Invest. 2021 Feb 15;131(4):e140299. doi: 10.1172/JCI140299. J Clin Invest. 2021. PMID: 33586677 Free PMC article.
113 results