Gielen O - Search Results

1

TAL1 cooperates with PI3K/AKT pathway activation in T-cell acute lymphoblastic leukemia.

Thielemans N, Demeyer S, Mentens N, Gielen O, Provost S, Cools J. Thielemans N, et al. Among authors: gielen o. Haematologica. 2022 Oct 1;107(10):2304-2317. doi: 10.3324/haematol.2021.279718. Haematologica. 2022. PMID: 35354248 Free PMC article.

2

Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.

De Keersmaecker K, Rocnik JL, Bernad R, Lee BH, Leeman D, Gielen O, Verachtert H, Folens C, Munck S, Marynen P, Fornerod M, Gilliland DG, Cools J. De Keersmaecker K, et al. Among authors: gielen o. Mol Cell. 2008 Jul 11;31(1):134-42. doi: 10.1016/j.molcel.2008.05.005. Mol Cell. 2008. PMID: 18614052 Free article.

3

JAK1 mutation analysis in T-cell acute lymphoblastic leukemia cell lines.

Porcu M, Gielen O, Cools J, De Keersmaecker K. Porcu M, et al. Among authors: gielen o. Haematologica. 2009 Mar;94(3):435-7. doi: 10.3324/haematol.13587. Epub 2009 Jan 27. Haematologica. 2009. PMID: 19176360 Free PMC article. No abstract available.

4

JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma.

Van Roosbroeck K, Cox L, Tousseyn T, Lahortiga I, Gielen O, Cauwelier B, De Paepe P, Verhoef G, Marynen P, Vandenberghe P, De Wolf-Peeters C, Cools J, Wlodarska I. Van Roosbroeck K, et al. Among authors: gielen o. Blood. 2011 Apr 14;117(15):4056-64. doi: 10.1182/blood-2010-06-291310. Epub 2011 Feb 15. Blood. 2011. PMID: 21325169 Free article.

5

Development of a siRNA and shRNA screening system based on a kinase fusion protein.

Pieraets S, Cox L, Gielen O, Cools J. Pieraets S, et al. Among authors: gielen o. RNA. 2012 Jun;18(6):1296-306. doi: 10.1261/rna.030015.111. Epub 2012 Apr 26. RNA. 2012. PMID: 22539522 Free PMC article.

6

NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.

De Keersmaecker K, Porcu M, Cox L, Girardi T, Vandepoel R, de Beeck JO, Gielen O, Mentens N, Bennett KL, Hantschel O. De Keersmaecker K, et al. Among authors: gielen o. Haematologica. 2014 Jan;99(1):85-93. doi: 10.3324/haematol.2013.088674. Epub 2013 Jul 19. Haematologica. 2014. PMID: 23872305 Free PMC article.

7

The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.

Noël LA, Arts FA, Montano-Almendras CP, Cox L, Gielen O, Toffalini F, Marbehant CY, Cools J, Demoulin JB. Noël LA, et al. Among authors: gielen o. Mol Oncol. 2014 May;8(3):728-40. doi: 10.1016/j.molonc.2014.02.003. Epub 2014 Feb 17. Mol Oncol. 2014. PMID: 24618081 Free PMC article.

8

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.

Degryse S, de Bock CE, Cox L, Demeyer S, Gielen O, Mentens N, Jacobs K, Geerdens E, Gianfelici V, Hulselmans G, Fiers M, Aerts S, Meijerink JP, Tousseyn T, Cools J. Degryse S, et al. Among authors: gielen o. Blood. 2014 Nov 13;124(20):3092-100. doi: 10.1182/blood-2014-04-566687. Epub 2014 Sep 5. Blood. 2014. PMID: 25193870 Free article.

9

Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.

Losdyck E, Hornakova T, Springuel L, Degryse S, Gielen O, Cools J, Constantinescu SN, Flex E, Tartaglia M, Renauld JC, Knoops L. Losdyck E, et al. Among authors: gielen o. J Biol Chem. 2015 Nov 27;290(48):29022-34. doi: 10.1074/jbc.M115.670224. Epub 2015 Oct 7. J Biol Chem. 2015. PMID: 26446793 Free PMC article.

10

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.

Dagklis A, Demeyer S, De Bie J, Radaelli E, Pauwels D, Degryse S, Gielen O, Vicente C, Vandepoel R, Geerdens E, Uyttebroeck A, Boeckx N, de Bock CE, Cools J. Dagklis A, et al. Among authors: gielen o. Blood. 2016 Dec 8;128(23):2642-2654. doi: 10.1182/blood-2016-03-703454. Epub 2016 Sep 30. Blood. 2016. PMID: 27694322 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

27 results

Search Page

Filters