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Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study.
de With M, Knikman J, de Man FM, Lunenburg CATC, Henricks LM, van Kuilenburg ABP, Maring JG, van Staveren MC, de Vries N, Rosing H, Beijnen JH, Pluim D, Modak A, Imholz ALT, van Schaik RHN, Schellens JHM, Gelderblom H, Cats A, Guchelaar HJ, Mathijssen RHJ, Swen JJ, Meulendijks D. de With M, et al. Among authors: modak a. Clin Pharmacol Ther. 2022 Jul;112(1):62-68. doi: 10.1002/cpt.2608. Epub 2022 May 4. Clin Pharmacol Ther. 2022. PMID: 35397172 Free PMC article.
Breath tests to phenotype drug disposition in oncology.
Opdam FL, Modak AS, Gelderblom H, Guchelaar HJ. Opdam FL, et al. Clin Pharmacokinet. 2013 Nov;52(11):919-26. doi: 10.1007/s40262-013-0099-9. Clin Pharmacokinet. 2013. PMID: 23868281 Review.
The use of the 13C-dextromethorphan breath test for phenotyping CYP2D6 in breast cancer patients using tamoxifen: association with CYP2D6 genotype and serum endoxifen levels.
Opdam FL, Dezentje VO, den Hartigh J, Modak AS, Vree R, Batman E, Smorenburg CH, Nortier JW, Gelderblom H, Guchelaar HJ. Opdam FL, et al. Among authors: modak as. Cancer Chemother Pharmacol. 2013 Mar;71(3):593-601. doi: 10.1007/s00280-012-2034-4. Epub 2012 Dec 11. Cancer Chemother Pharmacol. 2013. PMID: 23228987
454 results