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Short- and long-term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity.
Kvitne KE, Krogstad V, Wegler C, Johnson LK, Kringen MK, Hovd MH, Hertel JK, Heijer M, Sandbu R, Skovlund E, Artursson P, Karlsson C, Andersson S, Andersson TB, Hjelmesaeth J, Åsberg A, Jansson-Löfmark R, Christensen H, Robertsen I. Kvitne KE, et al. Among authors: karlsson c. Br J Clin Pharmacol. 2022 Sep;88(9):4121-4133. doi: 10.1111/bcp.15349. Epub 2022 Apr 25. Br J Clin Pharmacol. 2022. PMID: 35404513 Free PMC article. Clinical Trial.
Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL).
Hjelmesæth J, Åsberg A, Andersson S, Sandbu R, Robertsen I, Johnson LK, Angeles PC, Hertel JK, Skovlund E, Heijer M, Ek AL, Krogstad V, Karlsen TI, Christensen H, Andersson TB, Karlsson C. Hjelmesæth J, et al. Among authors: karlsson c. BMJ Open. 2018 May 29;8(5):e021878. doi: 10.1136/bmjopen-2018-021878. BMJ Open. 2018. PMID: 29844102 Free PMC article.
A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity.
Krogstad V, Peric A, Robertsen I, Kringen MK, Wegler C, Angeles PC, Hjelmesæth J, Karlsson C, Andersson S, Artursson P, Åsberg A, Andersson TB, Christensen H. Krogstad V, et al. Among authors: karlsson c. Drug Metab Dispos. 2020 Jan;48(1):8-17. doi: 10.1124/dmd.119.087940. Epub 2019 Nov 4. Drug Metab Dispos. 2020. PMID: 31685482
Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes.
Krogstad V, Peric A, Robertsen I, Kringen MK, Vistnes M, Hjelmesæth J, Sandbu R, Johnson LK, Angeles PC, Jansson-Löfmark R, Karlsson C, Andersson S, Åsberg A, Andersson TB, Christensen H. Krogstad V, et al. Among authors: karlsson c. J Pharm Sci. 2021 Jan;110(1):432-437. doi: 10.1016/j.xphs.2020.10.027. Epub 2020 Oct 19. J Pharm Sci. 2021. PMID: 33091408 Free article.
Short- and long-term effects of body weight loss following calorie restriction and gastric bypass on CYP3A-activity - a non-randomized three-armed controlled trial.
Kvitne KE, Robertsen I, Skovlund E, Christensen H, Krogstad V, Wegler C, Angeles PC, Wollmann BM, Hole K, Johnson LK, Sandbu R, Artursson P, Karlsson C, Andersson S, Andersson TB, Hjelmesaeth J, Jansson-Löfmark R, Åsberg A. Kvitne KE, et al. Among authors: karlsson c. Clin Transl Sci. 2022 Jan;15(1):221-233. doi: 10.1111/cts.13142. Epub 2021 Aug 26. Clin Transl Sci. 2022. PMID: 34435745 Free PMC article.
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range.
Eide Kvitne K, Hole K, Krogstad V, Wollmann BM, Wegler C, Johnson LK, Hertel JK, Artursson P, Karlsson C, Andersson S, Andersson TB, Sandbu R, Hjelmesæth J, Skovlund E, Christensen H, Jansson-Löfmark R, Åsberg A, Molden E, Robertsen I. Eide Kvitne K, et al. Among authors: karlsson c. Eur J Clin Pharmacol. 2022 Aug;78(8):1289-1299. doi: 10.1007/s00228-022-03336-9. Epub 2022 Jun 1. Eur J Clin Pharmacol. 2022. PMID: 35648149 Free PMC article.
Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity.
Kvitne KE, Åsberg A, Johnson LK, Wegler C, Hertel JK, Artursson P, Karlsson C, Andersson S, Sandbu R, Skovlund E, Christensen H, Jansson-Löfmark R, Hjelmesaeth J, Robertsen I. Kvitne KE, et al. Among authors: karlsson c. Clin Transl Sci. 2022 Nov;15(11):2685-2696. doi: 10.1111/cts.13394. Epub 2022 Sep 8. Clin Transl Sci. 2022. PMID: 36037309 Free PMC article.
Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance.
Hovd M, Robertsen I, Johnson LK, Krogstad V, Wegler C, Kvitne KE, Kringen MK, Skovlund E, Karlsson C, Andersson S, Artursson P, Sandbu R, Hjelmesæth J, Åsberg A, Jansson-Löfmark R, Christensen H. Hovd M, et al. Among authors: karlsson c. Clin Pharmacokinet. 2023 May;62(5):725-735. doi: 10.1007/s40262-023-01235-5. Epub 2023 Mar 29. Clin Pharmacokinet. 2023. PMID: 36988826 Free PMC article.
Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals.
Kvitne KE, Hovd M, Johnson LK, Wegler C, Karlsson C, Artursson P, Andersson S, Sandbu R, Hjelmesæth J, Skovlund E, Jansson-Löfmark R, Christensen H, Åsberg A, Robertsen I. Kvitne KE, et al. Among authors: karlsson c. Clin Pharmacokinet. 2024 Jan;63(1):109-120. doi: 10.1007/s40262-023-01320-9. Epub 2023 Nov 22. Clin Pharmacokinet. 2024. PMID: 37993699 Free PMC article.
438 results