Ramirez P - Search Results

1

Tau-induced deficits in nonsense-mediated mRNA decay contribute to neurodegeneration.

Zuniga G, Levy S, Ramirez P, De Mange J, Gonzalez E, Gamez M, Frost B. Zuniga G, et al. Among authors: ramirez p. Alzheimers Dement. 2023 Feb;19(2):405-420. doi: 10.1002/alz.12653. Epub 2022 Apr 13. Alzheimers Dement. 2023. PMID: 35416419 Free PMC article.

2

Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium.

Mahoney R, Ochoa Thomas E, Ramirez P, Miller HE, Beckmann A, Zuniga G, Dobrowolski R, Frost B. Mahoney R, et al. Among authors: ramirez p. Cell Rep. 2020 Jul 14;32(2):107900. doi: 10.1016/j.celrep.2020.107900. Cell Rep. 2020. PMID: 32668249 Free PMC article.

3

Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system.

Ramirez P, Zuniga G, Sun W, Beckmann A, Ochoa E, DeVos SL, Hyman B, Chiu G, Roy ER, Cao W, Orr M, Buggia-Prevot V, Ray WJ, Frost B. Ramirez P, et al. Prog Neurobiol. 2022 Jan;208:102181. doi: 10.1016/j.pneurobio.2021.102181. Epub 2021 Oct 17. Prog Neurobiol. 2022. PMID: 34670118 Free PMC article.

4

Tau-Induced Elevation of the Activity-Regulated Cytoskeleton Associated Protein Arc1 Causally Mediates Neurodegeneration in the Adult Drosophila Brain.

Schulz L, Ramirez P, Lemieux A, Gonzalez E, Thomson T, Frost B. Schulz L, et al. Among authors: ramirez p. Neuroscience. 2023 May 10;518:101-111. doi: 10.1016/j.neuroscience.2022.04.017. Epub 2022 Apr 27. Neuroscience. 2023. PMID: 35487302 Free PMC article.

5

Pathogenic tau-induced transposable element-derived dsRNA drives neuroinflammation.

Ochoa E, Ramirez P, Gonzalez E, De Mange J, Ray WJ, Bieniek KF, Frost B. Ochoa E, et al. Among authors: ramirez p. Sci Adv. 2023 Jan 6;9(1):eabq5423. doi: 10.1126/sciadv.abq5423. Epub 2023 Jan 6. Sci Adv. 2023. PMID: 36608133 Free PMC article.

6

Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer's disease.

Beckmann A, Ramirez P, Gamez M, Gonzalez E, De Mange J, Bieniek KF, Ray WJ, Frost B. Beckmann A, et al. Among authors: ramirez p. iScience. 2023 Feb 8;26(3):106152. doi: 10.1016/j.isci.2023.106152. eCollection 2023 Mar 17. iScience. 2023. PMID: 36879821 Free PMC article.

7

A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment.

Orr ME, Kotkowski E, Ramirez P, Bair-Kelps D, Liu Q, Brenner C, Schmidt MS, Fox PT, Larbi A, Tan C, Wong G, Gelfond J, Frost B, Espinoza S, Musi N, Powers B. Orr ME, et al. Among authors: ramirez p. Geroscience. 2024 Feb;46(1):665-682. doi: 10.1007/s11357-023-00999-9. Epub 2023 Nov 23. Geroscience. 2024. PMID: 37994989 Free PMC article. Clinical Trial.

8

m6A-dependent circular RNA formation mediates tau-induced neurotoxicity.

Atrian F, Ramirez P, De Mange J, Marquez M, Gonzalez EM, Minaya M, Karch CM, Frost B. Atrian F, et al. Among authors: ramirez p. bioRxiv [Preprint]. 2024 Jan 26:2024.01.25.577211. doi: 10.1101/2024.01.25.577211. bioRxiv. 2024. PMID: 38328044 Free PMC article. Preprint.

9

A pilot study to investigate the safety and feasibility of antiretroviral therapy for Alzheimer's disease (ART-AD).

Sullivan AC, Zuniga G, Ramirez P, Fernandez R, Wang CP, Li J, Davila L, Pelton K, Gomez S, Sohn C, Gonzalez E, Lopez-Cruzan M, Gonzalez DA, Parker A, Zilli E, de Erausquin GA, Seshadri S, Espinoza S, Musi N, Frost B. Sullivan AC, et al. Among authors: ramirez p. medRxiv [Preprint]. 2024 Feb 28:2024.02.26.24303316. doi: 10.1101/2024.02.26.24303316. medRxiv. 2024. PMID: 38464267 Free PMC article. Preprint.

10

Pathogenic tau induces an adaptive elevation in mRNA translation rate at early stages of disease.

Zuniga G, Katsumura S, De Mange J, Ramirez P, Atrian F, Morita M, Frost B. Zuniga G, et al. Among authors: ramirez p. Aging Cell. 2024 Oct;23(10):e14245. doi: 10.1111/acel.14245. Epub 2024 Jun 26. Aging Cell. 2024. PMID: 38932463 Free PMC article.

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