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Page 1
Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.
Bell JB, Eckerdt F, Dhruv HD, Finlay D, Peng S, Kim S, Kroczynska B, Beauchamp EM, Alley K, Clymer J, Goldman S, Cheng SY, James CD, Nakano I, Horbinski C, Mazar AP, Vuori K, Kumthekar P, Raizer J, Berens ME, Platanias LC. Bell JB, et al. Mol Cancer Res. 2018 Jan;16(1):32-46. doi: 10.1158/1541-7786.MCR-17-0397. Epub 2017 Oct 17. Mol Cancer Res. 2018. PMID: 29042487 Free PMC article.
IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.
Ladomersky E, Zhai L, Lenzen A, Lauing KL, Qian J, Scholtens DM, Gritsina G, Sun X, Liu Y, Yu F, Gong W, Liu Y, Jiang B, Tang T, Patel R, Platanias LC, James CD, Stupp R, Lukas RV, Binder DC, Wainwright DA. Ladomersky E, et al. Among authors: platanias lc. Clin Cancer Res. 2018 Jun 1;24(11):2559-2573. doi: 10.1158/1078-0432.CCR-17-3573. Epub 2018 Mar 2. Clin Cancer Res. 2018. PMID: 29500275 Free PMC article.
Myeloid-Derived Suppressive Cells Promote B cell-Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma.
Lee-Chang C, Rashidi A, Miska J, Zhang P, Pituch KC, Hou D, Xiao T, Fischietti M, Kang SJ, Appin CL, Horbinski C, Platanias LC, Lopez-Rosas A, Han Y, Balyasnikova IV, Lesniak MS. Lee-Chang C, et al. Among authors: platanias lc. Cancer Immunol Res. 2019 Dec;7(12):1928-1943. doi: 10.1158/2326-6066.CIR-19-0240. Epub 2019 Sep 17. Cancer Immunol Res. 2019. PMID: 31530559 Free PMC article.
Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma.
Fischietti M, Eckerdt F, Blyth GT, Arslan AD, Mati WM, Oku CV, Perez RE, Lee-Chang C, Kosciuczuk EM, Saleiro D, Beauchamp EM, Lesniak MS, Verzella D, Sun L, Fish EN, Yang GY, Qiang W, Platanias LC. Fischietti M, et al. Among authors: platanias lc. Oncogene. 2021 May;40(18):3273-3286. doi: 10.1038/s41388-021-01761-1. Epub 2021 Apr 12. Oncogene. 2021. PMID: 33846574 Free PMC article.
Glioblastoma as an age-related neurological disorder in adults.
Kim M, Ladomersky E, Mozny A, Kocherginsky M, O'Shea K, Reinstein ZZ, Zhai L, Bell A, Lauing KL, Bollu L, Rabin E, Dixit K, Kumthekar P, Platanias LC, Hou L, Zheng Y, Wu J, Zhang B, Hrachova M, Merrill SA, Mrugala MM, Prabhu VC, Horbinski C, James CD, Yamini B, Ostrom QT, Johnson MO, Reardon DA, Lukas RV, Wainwright DA. Kim M, et al. Among authors: platanias lc. Neurooncol Adv. 2021 Sep 4;3(1):vdab125. doi: 10.1093/noajnl/vdab125. eCollection 2021 Jan-Dec. Neurooncol Adv. 2021. PMID: 34647022 Free PMC article. Review.
Central nervous system immune interactome is a function of cancer lineage, tumor microenvironment, and STAT3 expression.
Najem H, Ott M, Kassab C, Rao A, Rao G, Marisetty A, Sonabend AM, Horbinski C, Verhaak R, Shankar A, Krishnan SN, Varn FS, Arrieta VA, Gupta P, Ferguson SD, Huse JT, Fuller GN, Long JP, Winkowski DE, Freiberg BA, James CD, Platanias LC, Lesniak MS, Burks JK, Heimberger AB. Najem H, et al. JCI Insight. 2022 May 9;7(9):e157612. doi: 10.1172/jci.insight.157612. JCI Insight. 2022. PMID: 35316217 Free PMC article.
SLFN11 negatively regulates non-canonical NFkB signaling to promote glioblastoma progression.
Fischietti M, Eckerdt F, Perez RE, Guillen Magaña JN, Mazewski C, Ho S, Gonzalez C, Streich LD, Beauchamp EM, Heimberger AB, Baran AH, Yue F, James CD, Platanias LC. Fischietti M, et al. Cancer Res Commun. 2022 Sep;2(9):966-978. doi: 10.1158/2767-9764.crc-22-0192. Epub 2022 Sep 13. Cancer Res Commun. 2022. PMID: 36382088 Free PMC article.
Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Bollu LR, Bommi PV, Monsen PJ, Zhai L, Lauing KL, Bell A, Kim M, Ladomersky E, Yang X, Platanias LC, Matei DE, Bonini MG, Munshi HG, Hashizume R, Wu JD, Zhang B, James CD, Chen P, Kocherginsky M, Horbinski C, Cameron MD, Grigorescu AA, Yamini B, Lukas RV, Schiltz GE, Wainwright DA. Bollu LR, et al. Among authors: platanias lc. J Med Chem. 2022 Dec 8;65(23):15642-15662. doi: 10.1021/acs.jmedchem.2c00771. Epub 2022 Nov 21. J Med Chem. 2022. PMID: 36410047 Free PMC article.
380 results