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T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex.
Hertweck A, Evans CM, Eskandarpour M, Lau JC, Oleinika K, Jackson I, Kelly A, Ambrose J, Adamson P, Cousins DJ, Lavender P, Calder VL, Lord GM, Jenner RG. Hertweck A, et al. Cell Rep. 2016 Jun 21;15(12):2756-70. doi: 10.1016/j.celrep.2016.05.054. Epub 2016 Jun 9. Cell Rep. 2016. PMID: 27292648 Free PMC article.
The Th1 cell regulatory circuitry is largely conserved between human and mouse.
Henderson S, Pullabhatla V, Hertweck A, de Rinaldis E, Herrero J, Lord GM, Jenner RG. Henderson S, et al. Among authors: hertweck a. Life Sci Alliance. 2021 Sep 16;4(11):e202101075. doi: 10.26508/lsa.202101075. Print 2021 Nov. Life Sci Alliance. 2021. PMID: 34531288 Free PMC article.
Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.
Soderquest K, Hertweck A, Giambartolomei C, Henderson S, Mohamed R, Goldberg R, Perucha E, Franke L, Herrero J, Plagnol V, Jenner RG, Lord GM. Soderquest K, et al. Among authors: hertweck a. PLoS Genet. 2017 Feb 10;13(2):e1006587. doi: 10.1371/journal.pgen.1006587. eCollection 2017 Feb. PLoS Genet. 2017. PMID: 28187197 Free PMC article.
A population of naive-like CD4+ T cells stably polarized to the TH 1 lineage.
Lo JW, de Mucha MV, Henderson S, Roberts LB, Constable LE, Garrido-Mesa N, Hertweck A, Stolarczyk E, Houlder EL, Jackson I, MacDonald AS, Powell N, Neves JF, Howard JK, Jenner RG, Lord GM. Lo JW, et al. Among authors: hertweck a. Eur J Immunol. 2022 Apr;52(4):566-581. doi: 10.1002/eji.202149228. Epub 2022 Feb 12. Eur J Immunol. 2022. PMID: 35092032 Free PMC article.
19 results