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Identification of HIV gp41-specific antibodies that mediate killing of infected cells.
Williams KL, Stumpf M, Naiman NE, Ding S, Garrett M, Gobillot T, Vézina D, Dusenbury K, Ramadoss NS, Basom R, Kim PS, Finzi A, Overbaugh J. Williams KL, et al. Among authors: vezina d. PLoS Pathog. 2019 Feb 19;15(2):e1007572. doi: 10.1371/journal.ppat.1007572. eCollection 2019 Feb. PLoS Pathog. 2019. PMID: 30779811 Free PMC article.
A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity.
Ding S, Grenier MC, Tolbert WD, Vézina D, Sherburn R, Richard J, Prévost J, Chapleau JP, Gendron-Lepage G, Medjahed H, Abrams C, Sodroski J, Pazgier M, Smith AB 3rd, Finzi A. Ding S, et al. Among authors: vezina d. J Virol. 2019 Nov 26;93(24):e01325-19. doi: 10.1128/JVI.01325-19. Print 2019 Dec 15. J Virol. 2019. PMID: 31554684 Free PMC article.
Optimization of Small Molecules That Sensitize HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity.
Grenier MC, Ding S, Vézina D, Chapleau JP, Tolbert WD, Sherburn R, Schön A, Somisetti S, Abrams CF, Pazgier M, Finzi A, Smith AB 3rd. Grenier MC, et al. Among authors: vezina d. ACS Med Chem Lett. 2019 Nov 15;11(3):371-378. doi: 10.1021/acsmedchemlett.9b00445. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184972 Free PMC article.
Stabilizing the HIV-1 envelope glycoprotein State 2A conformation.
Vézina D, Gong SY, Tolbert WD, Ding S, Nguyen D, Richard J, Gendron-Lepage G, Melillo B 3rd, Smith AB, Pazgier M, Finzi A. Vézina D, et al. J Virol. 2021 Mar 1;95(5):e01620-20. doi: 10.1128/JVI.01620-20. Epub 2020 Dec 9. J Virol. 2021. PMID: 33298541 Free PMC article.
A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: vezina d. bioRxiv [Preprint]. 2021 Mar 18:2021.03.18.435972. doi: 10.1101/2021.03.18.435972. bioRxiv. 2021. PMID: 33758857 Free PMC article. Preprint.
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.
Tauzin A, Nayrac M, Benlarbi M, Gong SY, Gasser R, Beaudoin-Bussières G, Brassard N, Laumaea A, Vézina D, Prévost J, Anand SP, Bourassa C, Gendron-Lepage G, Medjahed H, Goyette G, Niessl J, Tastet O, Gokool L, Morrisseau C, Arlotto P, Stamatatos L, McGuire AT, Larochelle C, Uchil P, Lu M, Mothes W, De Serres G, Moreira S, Roger M, Richard J, Martel-Laferrière V, Duerr R, Tremblay C, Kaufmann DE, Finzi A. Tauzin A, et al. Among authors: vezina d. Cell Host Microbe. 2021 Jul 14;29(7):1137-1150.e6. doi: 10.1016/j.chom.2021.06.001. Epub 2021 Jun 4. Cell Host Microbe. 2021. PMID: 34133950 Free PMC article.
Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern.
Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. Li W, et al. Among authors: vezina d. bioRxiv [Preprint]. 2021 Aug 3:2021.08.02.454546. doi: 10.1101/2021.08.02.454546. bioRxiv. 2021. Update in: Cell Rep. 2022 Jan 11;38(2):110210. doi: 10.1016/j.celrep.2021.110210 PMID: 34373853 Free PMC article. Updated. Preprint.
Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells.
Richard J, Nguyen DN, Tolbert WD, Gasser R, Ding S, Vézina D, Yu Gong S, Prévost J, Gendron-Lepage G, Medjahed H, Gottumukkala S, Finzi A, Pazgier M. Richard J, et al. Among authors: vezina d. mBio. 2021 Oct 26;12(5):e0140521. doi: 10.1128/mBio.01405-21. Epub 2021 Sep 28. mBio. 2021. PMID: 34579568 Free PMC article.
46 results