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Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab.
Alnajar H, Ravichandran H, Figueiredo Rendeiro A, Ohara K, Al Zoughbi W, Manohar J, Greco N, Sigouros M, Fox J, Muth E, Angiuoli S, Faltas B, Shusterman M, Sternberg CN, Elemento O, Mosquera JM. Alnajar H, et al. Among authors: ohara k. Cold Spring Harb Mol Case Stud. 2022 Apr 28;8(3):a006151. doi: 10.1101/mcs.a006151. Print 2022 Apr. Cold Spring Harb Mol Case Stud. 2022. PMID: 35483877 Free PMC article.
Fusions involving BCOR and CREBBP are rare events in infiltrating glioma.
Pisapia DJ, Ohara K, Bareja R, Wilkes DC, Hissong E, Croyle JA, Kim JH, Saab J, MacDonald TY, Beg S, O'Reilly C, Kudman S, Rubin MA, Elemento O, Sboner A, Greenfield J, Mosquera JM. Pisapia DJ, et al. Among authors: ohara k. Acta Neuropathol Commun. 2020 Jun 3;8(1):80. doi: 10.1186/s40478-020-00951-4. Acta Neuropathol Commun. 2020. PMID: 32493417 Free PMC article.
Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology.
Beg S, Bareja R, Ohara K, Eng KW, Wilkes DC, Pisapia DJ, Zoughbi WA, Kudman S, Zhang W, Rao R, Manohar J, Kane T, Sigouros M, Xiang JZ, Khani F, Robinson BD, Faltas BM, Sternberg CN, Sboner A, Beltran H, Elemento O, Mosquera JM. Beg S, et al. Among authors: ohara k. Transl Oncol. 2021 Jan;14(1):100944. doi: 10.1016/j.tranon.2020.100944. Epub 2020 Nov 12. Transl Oncol. 2021. PMID: 33190043 Free PMC article.
Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing.
Al Zoughbi W, Fox J, Beg S, Papp E, Hissong E, Ohara K, Keefer L, Sigouros M, Kane T, Bockelman D, Nichol D, Patchell E, Bareja R, Karandikar A, Alnajar H, Cerqueira G, Guthrie VB, Verner E, Manohar J, Greco N, Wilkes D, Tagawa S, Malbari MS, Holcomb K, Eng KW, Shah M, Altorki NK, Sboner A, Nanus D, Faltas B, Sternberg CN, Simmons J, Houvras Y, Molina AM, Angiuoli S, Elemento O, Mosquera JM. Al Zoughbi W, et al. Among authors: ohara k. Oncologist. 2021 Nov;26(11):e1971-e1981. doi: 10.1002/onco.13905. Epub 2021 Aug 4. Oncologist. 2021. PMID: 34286887 Free PMC article.
Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors.
Shohdy KS, Bareja R, Sigouros M, Wilkes DC, Dorsaint P, Manohar J, Bockelman D, Xiang JZ, Kim R, Ohara K, Eng K, Mosquera JM, Elemento O, Sboner A, Alonso A, Faltas BM. Shohdy KS, et al. Among authors: ohara k. NPJ Genom Med. 2021 Aug 12;6(1):66. doi: 10.1038/s41525-021-00231-7. NPJ Genom Med. 2021. PMID: 34385467 Free PMC article.
GLI1 -Rearranged Enteric Tumor : Expanding the Spectrum of Gastrointestinal Neoplasms With GLI1 Gene Fusions.
Jessurun J, Orr C, McNulty SN, Hagen CE, Alnajar H, Wilkes D, Kudman S, Al Assaad M, Dorsaint P, Ohara K, He F, Chiu K, Yin YM, Xiang JZ, Qin L, Sboner A, Elemento O, Yantiss RK, Graham RP, Poizat F, Mosquera JM. Jessurun J, et al. Among authors: ohara k. Am J Surg Pathol. 2023 Jan 1;47(1):65-73. doi: 10.1097/PAS.0000000000001950. Epub 2022 Aug 15. Am J Surg Pathol. 2023. PMID: 35968961
The evolution of metastatic upper tract urothelial carcinoma through genomic-transcriptomic and single-cell protein markers analysis.
Ohara K, Rendeiro AF, Bhinder B, Eng KW, Ravichandran H, Nguyen D, Pisapia D, Vosoughi A, Fernandez E, Shohdy KS, Manohar J, Beg S, Wilkes D, Robinson BD, Khani F, Bareja R, Tagawa ST, Ouseph MM, Sboner A, Elemento O, Faltas BM, Mosquera JM. Ohara K, et al. Nat Commun. 2024 Mar 18;15(1):2009. doi: 10.1038/s41467-024-46320-w. Nat Commun. 2024. PMID: 38499531 Free PMC article.
Integrative Transcriptomic and Single-Cell Protein Characterization of Colorectal Carcinoma Delineates Distinct Tumor Immune Microenvironments Associated with Overall Survival.
Hissong E, Bhinder B, Kim J, Ohara K, Ravichandran H, Assaad MA, Elsoukkary S, Shusterman M, Khan U, Eng KW, Bareja R, Manohar J, Sigouros M, Rendeiro AF, Jessurun J, Ocean AJ, Sboner A, Elemento O, Mosquera JM, Shah MA. Hissong E, et al. Among authors: ohara k. Res Sq [Preprint]. 2024 Jul 25:rs.3.rs-4751101. doi: 10.21203/rs.3.rs-4751101/v1. Res Sq. 2024. PMID: 39108491 Free PMC article. Preprint.
1,594 results