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S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
Pedraza-Chaverrí J, Barrera D, Maldonado PD, Chirino YI, Macías-Ruvalcaba NA, Medina-Campos ON, Castro L, Salcedo MI, Hernández-Pando R. Pedraza-Chaverrí J, et al. BMC Clin Pharmacol. 2004 Apr 30;4:5. doi: 10.1186/1472-6904-4-5. BMC Clin Pharmacol. 2004. PMID: 15119956 Free PMC article.
Selective iNOS inhibition reduces renal damage induced by cisplatin.
Chirino YI, Trujillo J, Sánchez-González DJ, Martínez-Martínez CM, Cruz C, Bobadilla NA, Pedraza-Chaverri J. Chirino YI, et al. Among authors: pedraza chaverri j. Toxicol Lett. 2008 Jan 4;176(1):48-57. doi: 10.1016/j.toxlet.2007.10.006. Epub 2007 Oct 24. Toxicol Lett. 2008. PMID: 18063323
Renoprotection by alpha-Mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity.
Pérez-Rojas JM, Cruz C, García-López P, Sánchez-González DJ, Martínez-Martínez CM, Ceballos G, Espinosa M, Meléndez-Zajgla J, Pedraza-Chaverri J. Pérez-Rojas JM, et al. Among authors: pedraza chaverri j. Free Radic Res. 2009;43(11):1122-32. doi: 10.1080/10715760903214447. Free Radic Res. 2009. PMID: 19863372
The alpha-mangostin prevention on cisplatin-induced apoptotic death in LLC-PK1 cells is associated to an inhibition of ROS production and p53 induction.
Sánchez-Pérez Y, Morales-Bárcenas R, García-Cuellar CM, López-Marure R, Calderon-Oliver M, Pedraza-Chaverri J, Chirino YI. Sánchez-Pérez Y, et al. Among authors: pedraza chaverri j. Chem Biol Interact. 2010 Oct 6;188(1):144-50. doi: 10.1016/j.cbi.2010.06.014. Chem Biol Interact. 2010. PMID: 20603111
470 results