Kuhn N - Search Results

1

Dopaminergic Positron Emission Tomography Imaging in the Alpha-Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease.

Sossi V, Patterson JR, McCormick S, Kemp CJ, Miller KM, Stoll AC, Kuhn N, Kubik M, Kochmanski J, Luk KC, Sortwell CE. Sossi V, et al. Among authors: kuhn n. Mov Disord. 2022 Aug;37(8):1739-1748. doi: 10.1002/mds.29051. Epub 2022 May 7. Mov Disord. 2022. PMID: 35524682 Free PMC article.

2

Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system.

Gombash SE, Manfredsson FP, Kemp CJ, Kuhn NC, Fleming SM, Egan AE, Grant LM, Ciucci MR, MacKeigan JP, Sortwell CE. Gombash SE, et al. PLoS One. 2013 Nov 27;8(11):e81426. doi: 10.1371/journal.pone.0081426. eCollection 2013. PLoS One. 2013. PMID: 24312298 Free PMC article.

3

Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain.

Polinski NK, Gombash SE, Manfredsson FP, Lipton JW, Kemp CJ, Cole-Strauss A, Kanaan NM, Steece-Collier K, Kuhn NC, Wohlgenant SL, Sortwell CE. Polinski NK, et al. Neurobiol Aging. 2015 Feb;36(2):1110-20. doi: 10.1016/j.neurobiolaging.2014.07.047. Epub 2014 Oct 13. Neurobiol Aging. 2015. PMID: 25457558 Free PMC article.

4

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.

Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Manfredsson FP, et al. Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16. Neurobiol Dis. 2018. PMID: 29341898 Free PMC article.

5

Basic Concepts in Viral Vector-Mediated Gene Therapy.

Benskey MJ, Sandoval IM, Miller K, Sellnow RL, Gezer A, Kuhn NC, Vashon R, Manfredsson FP. Benskey MJ, et al. Methods Mol Biol. 2019;1937:3-26. doi: 10.1007/978-1-4939-9065-8_1. Methods Mol Biol. 2019. PMID: 30706387

6

Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits.

Gezer AO, Kochmanski J, VanOeveren SE, Cole-Strauss A, Kemp CJ, Patterson JR, Miller KM, Kuhn NC, Herman DE, McIntire A, Lipton JW, Luk KC, Fleming SM, Sortwell CE, Bernstein AI. Gezer AO, et al. Neurobiol Dis. 2020 Jul;141:104947. doi: 10.1016/j.nbd.2020.104947. Epub 2020 May 15. Neurobiol Dis. 2020. PMID: 32422283 Free PMC article.

7

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling.

Patterson JR, Cole-Strauss A, Kuhn N, Mercier C, Kochmanski J, Gerlach JA, LeVeque RM, Neugebauer KA, Conner KN, Gomez J, Hennes MG, Thompson KE, Rytlewski DL, Bigwood CC, Scharmen A, Simjanovski G, Riley C, Donaldson J, Yasin D, Kouja N, Contejean Z, Burnett M, Aminova S, Yawson NA, Singh SB, Alian OM, Broeker CD, Zaluzec EK, ONeill M, Puschner B, Sousa A, Bix L, Jespersen B, Holzman C, Mitchell J, Julien R, Askin Y, Barnes D, Durshanpalli P, Krum D, Weber R, Patterson M, Anderson B, Hunt R, O'Brien B, Umstead A, Beck JS, Vega IE, Sortwell CE, Lipton JW. Patterson JR, et al. Among authors: kuhn n. J Vis Exp. 2022 Jun 23;(184). doi: 10.3791/64008. J Vis Exp. 2022. PMID: 35815999

8

Parkinson's disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons.

Kochmanski J, Kuhn NC, Bernstein AI. Kochmanski J, et al. NPJ Parkinsons Dis. 2022 Sep 23;8(1):120. doi: 10.1038/s41531-022-00355-2. NPJ Parkinsons Dis. 2022. PMID: 36151217 Free PMC article.

9

Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model.

Stoll AC, Kemp CJ, Patterson JR, Kubik M, Kuhn N, Benskey M, Duffy MF, Luk K, Sortwell CE. Stoll AC, et al. Among authors: kuhn n. Res Sq [Preprint]. 2023 May 4:rs.3.rs-2890683. doi: 10.21203/rs.3.rs-2890683/v1. Res Sq. 2023. PMID: 37205534 Free PMC article. Preprint.

10

Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice.

Boyd SL, Kuhn NC, Patterson JR, Stoll AC, Zimmerman SA, Kolanowski MR, Neubecker JJ, Luk KC, Ramsson ES, Sortwell CE, Bernstein AI. Boyd SL, et al. Toxicol Sci. 2023 Oct 30;196(1):99-111. doi: 10.1093/toxsci/kfad086. Toxicol Sci. 2023. PMID: 37607008 Free PMC article.

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