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11 results

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Page 1
Disease diagnostics using machine learning of immune receptors.
Zaslavsky ME, Craig E, Michuda JK, Sehgal N, Ram-Mohan N, Lee JY, Nguyen KD, Hoh RA, Pham TD, Röltgen K, Lam B, Parsons ES, Macwana SR, DeJager W, Drapeau EM, Roskin KM, Cunningham-Rundles C, Moody MA, Haynes BF, Goldman JD, Heath JR, Nadeau KC, Pinsky BA, Blish CA, Hensley SE, Jensen K, Meyer E, Balboni I, Utz PJ, Merrill JT, Guthridge JM, James JA, Yang S, Tibshirani R, Kundaje A, Boyd SD. Zaslavsky ME, et al. Among authors: dejager w. bioRxiv [Preprint]. 2024 Apr 3:2022.04.26.489314. doi: 10.1101/2022.04.26.489314. bioRxiv. 2024. PMID: 35547855 Free PMC article. Preprint.
Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study.
Guthridge JM, Lu R, Tran LT, Arriens C, Aberle T, Kamp S, Munroe ME, Dominguez N, Gross T, DeJager W, Macwana SR, Bourn RL, Apel S, Thanou A, Chen H, Chakravarty EF, Merrill JT, James JA. Guthridge JM, et al. Among authors: dejager w. EClinicalMedicine. 2020 Mar 4;20:100291. doi: 10.1016/j.eclinm.2020.100291. eCollection 2020 Mar. EClinicalMedicine. 2020. PMID: 32154507 Free PMC article.
Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus.
Wood RA, Guthridge L, Thurmond E, Guthridge CJ, Kheir JM, Bourn RL, Wagner CA, Chen H, DeJager W, Macwana SR, Kamp S, Lu R, Arriens C, Chakravarty EF, Thanou A, Merrill JT, Guthridge JM, James JA. Wood RA, et al. Among authors: dejager w. J Transl Autoimmun. 2021 Aug 31;4:100117. doi: 10.1016/j.jtauto.2021.100117. eCollection 2021. J Transl Autoimmun. 2021. PMID: 35005588 Free PMC article.
Genetic load in incomplete lupus erythematosus.
Slief M, Kheir JM, Smith M, Mowery C, Macwana S, DeJager W, Wagner CA, Aberle T, James JA, Guthridge JM. Slief M, et al. Among authors: dejager w. Lupus Sci Med. 2023 Jan;10(1):e000843. doi: 10.1136/lupus-2022-000843. Lupus Sci Med. 2023. PMID: 36599633 Free PMC article.
Ancestry-based differences in the immune phenotype are associated with lupus activity.
Slight-Webb S, Thomas K, Smith M, Wagner CA, Macwana S, Bylinska A, Donato M, Dvorak M, Chang SE, Kuo A, Cheung P, Kalesinskas L, Ganesan A, Dermadi D, Guthridge CJ, DeJager W, Wright C, Foecke MH, Merrill JT, Chakravarty E, Arriens C, Maecker HT, Khatri P, Utz PJ, James JA, Guthridge JM. Slight-Webb S, et al. Among authors: dejager w. JCI Insight. 2023 Aug 22;8(16):e169584. doi: 10.1172/jci.insight.169584. JCI Insight. 2023. PMID: 37606045 Free PMC article.
Biomarker panel increases accuracy for identification of an MS relapse beyond sNfL.
Gawde S, Agasing A, Bhatt N, Toliver M, Kumar G, Massey K, Nguyen A, Mao-Draayer Y, Macwana S, DeJager W, Guthridge JM, Pardo G, Dunn J, Axtell RC. Gawde S, et al. Among authors: dejager w. Mult Scler Relat Disord. 2022 Jul;63:103922. doi: 10.1016/j.msard.2022.103922. Epub 2022 May 28. Mult Scler Relat Disord. 2022. PMID: 35671674 Free PMC article.
Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.
Vanderlinden LA, Bemis EA, Seifert J, Guthridge JM, Young KA, Demoruelle MK, Feser M, DeJager W, Macwana S, Mikuls TR, O'Dell JR, Weisman MH, Buckner J, Keating RM, Gaffney PM, Kelly JA, Langefeld CD, Deane KD, James JA, Holers VM, Norris JM. Vanderlinden LA, et al. Among authors: dejager w. Front Immunol. 2022 Jun 3;13:881332. doi: 10.3389/fimmu.2022.881332. eCollection 2022. Front Immunol. 2022. PMID: 35720397 Free PMC article.
A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus.
Munroe ME, Blankenship D, DeFreese D, Purushothaman M, DeJager W, Macwana S, Guthridge JM, Kamp S, Redinger N, Aberle T, Chakravarty EF, Arriens C, Li Y, Zeng H, McCarthy-Fruin KA, Osei-Onomahm SA, Thanarajasingam U, James JA, Jupe E. Munroe ME, et al. Among authors: dejager w. Arthritis Rheumatol. 2023 May;75(5):723-735. doi: 10.1002/art.42389. Epub 2023 Mar 6. Arthritis Rheumatol. 2023. PMID: 36245261 Free PMC article.
Association of Autoantibody Concentrations and Trajectories With Lupus Nephritis Histologic Features and Treatment Response.
Fava A, Wagner CA, Guthridge CJ, Kheir J, Macwana S, DeJager W, Gross T, Izmirly P, Belmont HM, Diamond B, Davidson A, Utz PJ, Weisman MH, Magder LS; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Guthridge JM, Petri M, Buyon J, James JA. Fava A, et al. Among authors: dejager w. Arthritis Rheumatol. 2024 Nov;76(11):1611-1622. doi: 10.1002/art.42941. Epub 2024 Aug 9. Arthritis Rheumatol. 2024. PMID: 38962936
Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network.
Deonaraine KK, Carlucci PM, Fava A, Li J, Wofsy D, James JA, Putterman C, Diamond B, Davidson A, Fine DM, Monroy-Trujillo J, Atta MG, Haag K, Rao DA, Apruzzese W, Belmont HM, Izmirly PM, Wu M, Connery S, Payan-Schober F, Furie RA, Berthier CC, Dall'Era M, Cho K, Kamen DL, Kalunian K, Anolik J, Ishimori M, Weisman MH; Accelerating Medicines Partnership RA/SLE network; Petri MA, Buyon JP. Deonaraine KK, et al. Lupus Sci Med. 2021 Aug;8(1):e000522. doi: 10.1136/lupus-2021-000522. Lupus Sci Med. 2021. PMID: 34389634 Free PMC article.
11 results