Spengler K - Search Results

1

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.

Ovens AJ, Gee YS, Ling NXY, Yu D, Hardee JP, Chung JD, Ngoei KRW, Waters NJ, Hoffman NJ, Scott JW, Loh K, Spengler K, Heller R, Parker MW, Lynch GS, Huang F, Galic S, Kemp BE, Baell JB, Oakhill JS, Langendorf CG. Ovens AJ, et al. Among authors: spengler k. Biochem J. 2022 Jun 17;479(11):1181-1204. doi: 10.1042/BCJ20220067. Biochem J. 2022. PMID: 35552369 Free PMC article.

2

Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase.

Stahmann N, Woods A, Spengler K, Heslegrave A, Bauer R, Krause S, Viollet B, Carling D, Heller R. Stahmann N, et al. Among authors: spengler k. J Biol Chem. 2010 Apr 2;285(14):10638-52. doi: 10.1074/jbc.M110.108688. Epub 2010 Feb 3. J Biol Chem. 2010. PMID: 20129920 Free PMC article.

3

Maternal diabetes promotes mTORC1 downstream signalling in rabbit preimplantation embryos.

Gürke J, Schindler M, Pendzialek SM, Thieme R, Grybel KJ, Heller R, Spengler K, Fleming TP, Fischer B, Navarrete Santos A. Gürke J, et al. Among authors: spengler k. Reproduction. 2016 May;151(5):465-76. doi: 10.1530/REP-15-0523. Epub 2016 Feb 1. Reproduction. 2016. PMID: 26836250

4

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis.

Zibrova D, Vandermoere F, Göransson O, Peggie M, Mariño KV, Knierim A, Spengler K, Weigert C, Viollet B, Morrice NA, Sakamoto K, Heller R. Zibrova D, et al. Among authors: spengler k. Biochem J. 2017 Mar 7;474(6):983-1001. doi: 10.1042/BCJ20160980. Biochem J. 2017. PMID: 28008135 Free article.

5

Studying the Role of AMPK in Angiogenesis.

Spengler K, Große S, Kryeziu N, Knierim A, Heller R. Spengler K, et al. Methods Mol Biol. 2018;1732:519-537. doi: 10.1007/978-1-4939-7598-3_33. Methods Mol Biol. 2018. PMID: 29480497

6

VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1.

Spengler K, Kryeziu N, Große S, Mosig AS, Heller R. Spengler K, et al. Cells. 2020 Mar 11;9(3):687. doi: 10.3390/cells9030687. Cells. 2020. PMID: 32168879 Free PMC article.

7

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495.

Spengler K, Zibrova D, Woods A, Langendorf CG, Scott JW, Carling D, Heller R. Spengler K, et al. Biochem J. 2020 Sep 18;477(17):3453-3469. doi: 10.1042/BCJ20200555. Biochem J. 2020. PMID: 32869834

8

Oxidative Glucose Metabolism Promotes Senescence in Vascular Endothelial Cells.

Stabenow LK, Zibrova D, Ender C, Helbing DL, Spengler K, Marx C, Wang ZQ, Heller R. Stabenow LK, et al. Among authors: spengler k. Cells. 2022 Jul 16;11(14):2213. doi: 10.3390/cells11142213. Cells. 2022. PMID: 35883656 Free PMC article.

9

AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1.

Doshi H, Spengler K, Godbole A, Gee YS, Baell J, Oakhill JS, Henke A, Heller R. Doshi H, et al. Among authors: spengler k. Microbiol Spectr. 2023 Sep 13;11(5):e0041723. doi: 10.1128/spectrum.00417-23. Online ahead of print. Microbiol Spectr. 2023. PMID: 37702499 Free PMC article.

10

Influence of sphingosine-1-phosphate signaling on HCMV replication in human embryonal lung fibroblasts.

Zilch A, Rien C, Weigel C, Huskobla S, Glück B, Spengler K, Sauerbrei A, Heller R, Gräler M, Henke A. Zilch A, et al. Among authors: spengler k. Med Microbiol Immunol. 2018 Aug;207(3-4):227-242. doi: 10.1007/s00430-018-0543-4. Epub 2018 Apr 26. Med Microbiol Immunol. 2018. PMID: 29700602

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