Koyama N - Search Results

1

Optimizing machine-learning models for mutagenicity prediction through better feature selection.

Shinada NK, Koyama N, Ikemori M, Nishioka T, Hitaoka S, Hakura A, Asakura S, Matsuoka Y, Palaniappan SK. Shinada NK, et al. Among authors: koyama n. Mutagenesis. 2022 Oct 26;37(3-4):191-202. doi: 10.1093/mutage/geac010. Mutagenesis. 2022. PMID: 35554560

2

o-Aminoazotoluene, 7,12-dimethylbenz[a]anthracene, and N-ethyl-N-nitrosourea, which are mutagenic but not carcinogenic in the colon, rapidly induce colonic tumors in mice with dextran sulfate sodium-induced colitis.

Hakura A, Koyama N, Seki Y, Sonoda J, Asakura S. Hakura A, et al. Among authors: koyama n. Genes Environ. 2022 Mar 29;44(1):11. doi: 10.1186/s41021-022-00240-7. Genes Environ. 2022. PMID: 35351212 Free PMC article.

3

Evaluation of acetone as a solvent for the Ames test.

Shibata T, Yamagata T, Kawade A, Asakura S, Toritsuka N, Koyama N, Hakura A. Shibata T, et al. Among authors: koyama n. Genes Environ. 2020 Jan 23;42:3. doi: 10.1186/s41021-020-0143-6. eCollection 2020. Genes Environ. 2020. PMID: 31998422 Free PMC article.

4

Wif1 and Ifitm3 gene expression preferentially altered in the colon mucosa of benzo[a]pyrene pre-treated mice following exposure to dextran sulfate sodium.

Koyama N, Hakura A, Toritsuka N, Sonoda J, Seki Y, Tohyama O, Asakura S, Nakano-Ito K, Hosokawa S. Koyama N, et al. Chem Biol Interact. 2015 Oct 5;240:164-70. doi: 10.1016/j.cbi.2015.07.012. Epub 2015 Aug 10. Chem Biol Interact. 2015. PMID: 26271895

5

Acrylamide genotoxicity in young versus adult gpt delta male rats.

Koyama N, Yasui M, Kimura A, Takami S, Suzuki T, Masumura K, Nohmi T, Masuda S, Kinae N, Matsuda T, Imai T, Honma M. Koyama N, et al. Mutagenesis. 2011 Jul;26(4):545-9. doi: 10.1093/mutage/ger014. Epub 2011 Mar 25. Mutagenesis. 2011. PMID: 21441395

6

A comparison of the lowest effective concentration in culture media for detection of chromosomal damage in vitro and in blood or plasma for detection of micronuclei in vivo.

Kirkland D, Whitwell J, Smith R, Hashimoto K, Ji Z, Kenny J, Koyama N, Lovell DP, Martus HJ, Meurer K, Roberts D, Takeiri A, Uno Y, van der Leede BJ, White P, Zeller A. Kirkland D, et al. Among authors: koyama n. Mutat Res Genet Toxicol Environ Mutagen. 2022 Jul-Aug;879-880:503503. doi: 10.1016/j.mrgentox.2022.503503. Epub 2022 May 28. Mutat Res Genet Toxicol Environ Mutagen. 2022. PMID: 35914859 Free article.

7

Genotoxicity of acrylamide in vitro: Acrylamide is not metabolically activated in standard in vitro systems.

Koyama N, Yasui M, Oda Y, Suzuki S, Satoh T, Suzuki T, Matsuda T, Masuda S, Kinae N, Honma M. Koyama N, et al. Environ Mol Mutagen. 2011 Jan;52(1):11-9. doi: 10.1002/em.20560. Environ Mol Mutagen. 2011. PMID: 20209648

8

Malaria in cynomolgus monkeys used in toxicity studies in Japan.

Ohta E, Nagayama Y, Koyama N, Kakiuchi D, Hosokawa S. Ohta E, et al. Among authors: koyama n. J Toxicol Pathol. 2016 Jan;29(1):31-8. doi: 10.1293/tox.2015-0051. Epub 2015 Nov 20. J Toxicol Pathol. 2016. PMID: 26989299 Free PMC article.

9

Genotoxicity of acrylamide and glycidamide in human lymphoblastoid TK6 cells.

Koyama N, Sakamoto H, Sakuraba M, Koizumi T, Takashima Y, Hayashi M, Matsufuji H, Yamagata K, Masuda S, Kinae N, Honma M. Koyama N, et al. Mutat Res. 2006 Feb 28;603(2):151-8. doi: 10.1016/j.mrgentox.2005.11.006. Epub 2006 Jan 18. Mutat Res. 2006. PMID: 16387526

10

Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.

Yasui M, Suenaga E, Koyama N, Masutani C, Hanaoka F, Gruz P, Shibutani S, Nohmi T, Hayashi M, Honma M. Yasui M, et al. Among authors: koyama n. J Mol Biol. 2008 Apr 4;377(4):1015-23. doi: 10.1016/j.jmb.2008.01.033. Epub 2008 Jan 18. J Mol Biol. 2008. PMID: 18304575

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