Chintha C - Search Results

1

Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1.

Chintha C, Carlesso A, Gorman AM, Samali A, Eriksson LA. Chintha C, et al. RSC Adv. 2020 Jan 2;10(1):367-375. doi: 10.1039/c9ra08047c. eCollection 2019 Dec 20. RSC Adv. 2020. PMID: 35558862 Free PMC article.

2

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain.

Carlesso A, Chintha C, Gorman AM, Samali A, Eriksson LA. Carlesso A, et al. Among authors: chintha c. ACS Omega. 2018 Oct 31;3(10):13313-13322. doi: 10.1021/acsomega.8b01404. Epub 2018 Oct 16. ACS Omega. 2018. PMID: 30411035 Free PMC article.

3

Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors.

Carlesso A, Chintha C, Gorman AM, Samali A, Eriksson LA. Carlesso A, et al. Among authors: chintha c. Sci Rep. 2019 Mar 4;9(1):3407. doi: 10.1038/s41598-019-39939-z. Sci Rep. 2019. PMID: 30833722 Free PMC article.

4

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.

Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy WS, Chintha C, Schubert T, Samali A, Chevet E, Eriksson LA, Huber M, Tirosh B. Mahameed M, et al. Among authors: chintha c. Cell Death Dis. 2019 Apr 1;10(4):300. doi: 10.1038/s41419-019-1523-3. Cell Death Dis. 2019. PMID: 30931942 Free PMC article.

5

Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling.

Carlesso A, Chintha C, Gorman AM, Samali A, Eriksson LA. Carlesso A, et al. Among authors: chintha c. Int J Mol Sci. 2019 Nov 6;20(22):5538. doi: 10.3390/ijms20225538. Int J Mol Sci. 2019. PMID: 31698846 Free PMC article.

6

Peptidomimetic-based identification of FDA-approved compounds inhibiting IRE1 activity.

Doultsinos D, Carlesso A, Chintha C, Paton JC, Paton AW, Samali A, Chevet E, Eriksson LA. Doultsinos D, et al. Among authors: chintha c. FEBS J. 2021 Feb;288(3):945-960. doi: 10.1111/febs.15372. Epub 2020 Jun 11. FEBS J. 2021. PMID: 32446294 Free article.

7

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications.

Almanza A, Carlesso A, Chintha C, Creedican S, Doultsinos D, Leuzzi B, Luís A, McCarthy N, Montibeller L, More S, Papaioannou A, Püschel F, Sassano ML, Skoko J, Agostinis P, de Belleroche J, Eriksson LA, Fulda S, Gorman AM, Healy S, Kozlov A, Muñoz-Pinedo C, Rehm M, Chevet E, Samali A. Almanza A, et al. Among authors: chintha c. FEBS J. 2019 Jan;286(2):241-278. doi: 10.1111/febs.14608. Epub 2018 Aug 4. FEBS J. 2019. PMID: 30027602 Free PMC article. Review.

8

Novel Pt(IV) Prodrugs Displaying Antimitochondrial Effects.

Tabrizi L, Thompson K, Mnich K, Chintha C, Gorman AM, Morrison L, Luessing J, Lowndes NF, Dockery P, Samali A, Erxleben A. Tabrizi L, et al. Among authors: chintha c. Mol Pharm. 2020 Aug 3;17(8):3009-3023. doi: 10.1021/acs.molpharmaceut.0c00417. Epub 2020 Jul 15. Mol Pharm. 2020. PMID: 32628022

9

Gold(I) Complexes with a Quinazoline Carboxamide Alkynyl Ligand: Synthesis, Cytotoxicity, and Mechanistic Studies.

Tabrizi L, Yang WS, Chintha C, Morrison L, Samali A, Ramos JW, Erxleben A. Tabrizi L, et al. Among authors: chintha c. Eur J Inorg Chem. 2021 May 26;2021(20):1921-1928. doi: 10.1002/ejic.202100120. Epub 2021 May 11. Eur J Inorg Chem. 2021. PMID: 34248416 Free PMC article.

10

Homology modeling a fast tool for drug discovery: current perspectives.

Vyas VK, Ukawala RD, Ghate M, Chintha C. Vyas VK, et al. Among authors: chintha c. Indian J Pharm Sci. 2012 Jan;74(1):1-17. doi: 10.4103/0250-474X.102537. Indian J Pharm Sci. 2012. PMID: 23204616 Free PMC article.

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