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Hydroxylation and dechlorination of 3,3',4,4'-tetrachlorobiphenyl (CB77) by rat and human CYP1A1s and critical roles of amino acids composing their substrate-binding cavity.
Yabu M, Haga Y, Itoh T, Goto E, Suzuki M, Yamazaki K, Mise S, Yamamoto K, Matsumura C, Nakano T, Sakaki T, Inui H. Yabu M, et al. Among authors: yamamoto k. Sci Total Environ. 2022 Sep 1;837:155848. doi: 10.1016/j.scitotenv.2022.155848. Epub 2022 May 11. Sci Total Environ. 2022. PMID: 35568185
Metabolism of vitamin D3 by cytochromes P450.
Sakaki T, Kagawa N, Yamamoto K, Inouye K. Sakaki T, et al. Among authors: yamamoto k. Front Biosci. 2005 Jan 1;10:119-34. doi: 10.2741/1514. Print 2005 Jan 1. Front Biosci. 2005. PMID: 15574355 Review.
Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats.
Hamamoto H, Kusudo T, Urushino N, Masuno H, Yamamoto K, Yamada S, Kamakura M, Ohta M, Inouye K, Sakaki T. Hamamoto H, et al. Among authors: yamamoto k. Mol Pharmacol. 2006 Jul;70(1):120-8. doi: 10.1124/mol.106.023275. Epub 2006 Apr 14. Mol Pharmacol. 2006. PMID: 16617161
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