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Transfusing Convalescent Plasma as Post-Exposure Prophylaxis Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Double-Blinded, Phase 2 Randomized, Controlled Trial.
Shoham S, Bloch EM, Casadevall A, Hanley D, Lau B, Gebo K, Cachay E, Kassaye SG, Paxton JH, Gerber J, Levine AC, Naeim A, Currier J, Patel B, Allen ES, Anjan S, Appel L, Baksh S, Blair PW, Bowen A, Broderick P, Caputo CA, Cluzet V, Cordisco ME, Cruser D, Ehrhardt S, Forthal D, Fukuta Y, Gawad AL, Gniadek T, Hammel J, Huaman MA, Jabs DA, Jedlicka A, Karlen N, Klein S, Laeyendecker O, Lane K, McBee N, Meisenberg B, Merlo C, Mosnaim G, Park HS, Pekosz A, Petrini J, Rausch W, Shade DM, Shapiro JR, Singleton JR, Sutcliffe C, Thomas DL, Yarava A, Zand M, Zenilman JM, Tobian AAR, Sullivan DJ. Shoham S, et al. Clin Infect Dis. 2023 Feb 8;76(3):e477-e486. doi: 10.1093/cid/ciac372. Clin Infect Dis. 2023. PMID: 35579509 Free PMC article. Clinical Trial.
MSG-01: A randomized, double-blind, placebo-controlled trial of caspofungin prophylaxis followed by preemptive therapy for invasive candidiasis in high-risk adults in the critical care setting.
Ostrosky-Zeichner L, Shoham S, Vazquez J, Reboli A, Betts R, Barron MA, Schuster M, Judson MA, Revankar SG, Caeiro JP, Mangino JE, Mushatt D, Bedimo R, Freifeld A, Nguyen MH, Kauffman CA, Dismukes WE, Westfall AO, Deerman JB, Wood C, Sobel JD, Pappas PG. Ostrosky-Zeichner L, et al. Among authors: shoham s. Clin Infect Dis. 2014 May;58(9):1219-26. doi: 10.1093/cid/ciu074. Epub 2014 Feb 18. Clin Infect Dis. 2014. PMID: 24550378 Clinical Trial.
A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic Cell Transplant Recipients with Respiratory Syncytial Virus Infection of the Lower Respiratory Tract.
Marty FM, Chemaly RF, Mullane KM, Lee DG, Hirsch HH, Small CB, Bergeron A, Shoham S, Ljungman P, Waghmare A, Blanchard E, Kim YJ, McKevitt M, Porter DP, Jordan R, Guo Y, German P, Boeckh M, Watkins TR, Chien JW, Dadwal SS. Marty FM, et al. Among authors: shoham s. Clin Infect Dis. 2020 Dec 31;71(11):2787-2795. doi: 10.1093/cid/ciz1167. Clin Infect Dis. 2020. PMID: 31915807 Free PMC article. Clinical Trial.
Deployment of convalescent plasma for the prevention and treatment of COVID-19.
Bloch EM, Shoham S, Casadevall A, Sachais BS, Shaz B, Winters JL, van Buskirk C, Grossman BJ, Joyner M, Henderson JP, Pekosz A, Lau B, Wesolowski A, Katz L, Shan H, Auwaerter PG, Thomas D, Sullivan DJ, Paneth N, Gehrie E, Spitalnik S, Hod EA, Pollack L, Nicholson WT, Pirofski LA, Bailey JA, Tobian AA. Bloch EM, et al. Among authors: shoham s. J Clin Invest. 2020 Jun 1;130(6):2757-2765. doi: 10.1172/JCI138745. J Clin Invest. 2020. PMID: 32254064 Free PMC article. Review.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein S, Pekosz A, Park HS, Ursin R, Shapiro J, Benner S, Littlefield K, Kumar S, Naik HM, Betenbaugh M, Shrestha R, Wu A, Hughes R, Burgess I, Caturegli P, Laeyendecker O, Quinn T, Sullivan D, Shoham S, Redd A, Bloch E, Casadevall A, Tobian A. Klein S, et al. Among authors: shoham s. medRxiv [Preprint]. 2020 Jun 28:2020.06.26.20139063. doi: 10.1101/2020.06.26.20139063. medRxiv. 2020. Update in: J Clin Invest. 2020 Nov 2;130(11):6141-6150. doi: 10.1172/JCI142004. PMID: 32607519 Free PMC article. Updated. Preprint.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein SL, Pekosz A, Park HS, Ursin RL, Shapiro JR, Benner SE, Littlefield K, Kumar S, Naik HM, Betenbaugh MJ, Shrestha R, Wu AA, Hughes RM, Burgess I, Caturegli P, Laeyendecker O, Quinn TC, Sullivan D, Shoham S, Redd AD, Bloch EM, Casadevall A, Tobian AA. Klein SL, et al. Among authors: shoham s. J Clin Invest. 2020 Nov 2;130(11):6141-6150. doi: 10.1172/JCI142004. J Clin Invest. 2020. PMID: 32764200 Free PMC article.
Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O. Patel EU, et al. Among authors: shoham s. medRxiv [Preprint]. 2020 Sep 2:2020.08.31.20184788. doi: 10.1101/2020.08.31.20184788. medRxiv. 2020. Update in: J Clin Microbiol. 2021 Jan 21;59(2):e02257-20. doi: 10.1128/JCM.02257-20. PMID: 32908987 Free PMC article. Updated. Preprint.
SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors.
Benner SE, Patel EU, Laeyendecker O, Pekosz A, Littlefield K, Eby Y, Fernandez RE, Miller J, Kirby CS, Keruly M, Klock E, Baker OR, Schmidt HA, Shrestha R, Burgess I, Bonny TS, Clarke W, Caturegli P, Sullivan D, Shoham S, Quinn TC, Bloch EM, Casadevall A, Tobian AAR, Redd AD. Benner SE, et al. Among authors: shoham s. J Infect Dis. 2020 Nov 13;222(12):1974-1984. doi: 10.1093/infdis/jiaa581. J Infect Dis. 2020. PMID: 32910175 Free PMC article.
SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy.
Natarajan H, Crowley AR, Butler SE, Xu S, Weiner JA, Bloch EM, Littlefield K, Wieland-Alter W, Connor RI, Wright PF, Benner SE, Bonny TS, Laeyendecker O, Sullivan D, Shoham S, Quinn TC, Larman HB, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Ackerman ME. Natarajan H, et al. Among authors: shoham s. medRxiv [Preprint]. 2020 Sep 18:2020.09.16.20196154. doi: 10.1101/2020.09.16.20196154. medRxiv. 2020. PMID: 32995801 Free PMC article. Updated. Preprint.
CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entire SARS-CoV-2 proteome and show kinetics of early differentiation.
Kared H, Redd AD, Bloch EM, Bonny TS, Sumatoh H, Kairi F, Carbajo D, Abel B, Newell EW, Bettinotti MP, Benner SE, Patel EU, Littlefield K, Laeyendecker O, Shoham S, Sullivan D, Casadevall A, Pekosz A, Nardin A, Fehlings M, Tobian AA, Quinn TC. Kared H, et al. Among authors: shoham s. bioRxiv [Preprint]. 2020 Oct 8:2020.10.08.330688. doi: 10.1101/2020.10.08.330688. bioRxiv. 2020. PMID: 33052343 Free PMC article. Preprint.
339 results