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Page 1
Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Davidson SM, Schmidt DR, Heyman JE, O'Brien JP, Liu AC, Israelsen WJ, Dayton TL, Sehgal R, Bronson RT, Freinkman E, Mak HH, Fanelli GN, Malstrom S, Bellinger G, Carracedo A, Pandolfi PP, Courtney KD, Jha A, DePinho RA, Horner JW, Thomas CJ, Cantley LC, Loda M, Vander Heiden MG. Davidson SM, et al. Among authors: o brien jp. Cancer Res. 2022 Jul 5;82(13):2403-2416. doi: 10.1158/0008-5472.CAN-21-2352. Cancer Res. 2022. PMID: 35584006 Free PMC article.
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.
Davidson SM, Papagiannakopoulos T, Olenchock BA, Heyman JE, Keibler MA, Luengo A, Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L, Chin CR, Stephanopolous G, Mott BT, Jacks T, Clish CB, Vander Heiden MG. Davidson SM, et al. Cell Metab. 2016 Mar 8;23(3):517-28. doi: 10.1016/j.cmet.2016.01.007. Epub 2016 Feb 4. Cell Metab. 2016. PMID: 26853747 Free PMC article.
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL. Koudelka A, et al. Among authors: o brien jp. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579101. doi: 10.1101/2024.02.06.579101. bioRxiv. 2024. Update in: J Lipid Res. 2024 Nov 18:100705. doi: 10.1016/j.jlr.2024.100705 PMID: 38370667 Free PMC article. Updated. Preprint.
A 300-fold conductivity increase in microbial cytochrome nanowires due to temperature-induced restructuring of hydrogen bonding networks.
Dahl PJ, Yi SM, Gu Y, Acharya A, Shipps C, Neu J, O'Brien JP, Morzan UN, Chaudhuri S, Guberman-Pfeffer MJ, Vu D, Yalcin SE, Batista VS, Malvankar NS. Dahl PJ, et al. Among authors: o brien jp. Sci Adv. 2022 May 13;8(19):eabm7193. doi: 10.1126/sciadv.abm7193. Epub 2022 May 11. Sci Adv. 2022. PMID: 35544567 Free PMC article.
Protein nanowires with tunable functionality and programmable self-assembly using sequence-controlled synthesis.
Shapiro DM, Mandava G, Yalcin SE, Arranz-Gibert P, Dahl PJ, Shipps C, Gu Y, Srikanth V, Salazar-Morales AI, O'Brien JP, Vanderschuren K, Vu D, Batista VS, Malvankar NS, Isaacs FJ. Shapiro DM, et al. Among authors: o brien jp. Nat Commun. 2022 Feb 11;13(1):829. doi: 10.1038/s41467-022-28206-x. Nat Commun. 2022. PMID: 35149672 Free PMC article.
Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Manni ML, Heinrich VA, Buchan GJ, O'Brien JP, Uvalle C, Cechova V, Koudelka A, Ukani D, Rawas-Qalaji M, Oury TD, Hart R, Ellgass M, Mullett SJ, Fajt ML, Wenzel SE, Holguin F, Freeman BA, Wendell SG. Manni ML, et al. Among authors: o brien jp. Sci Rep. 2021 Sep 7;11(1):17788. doi: 10.1038/s41598-021-96471-9. Sci Rep. 2021. PMID: 34493738 Free PMC article.
Structure of Geobacter pili reveals secretory rather than nanowire behaviour.
Gu Y, Srikanth V, Salazar-Morales AI, Jain R, O'Brien JP, Yi SM, Soni RK, Samatey FA, Yalcin SE, Malvankar NS. Gu Y, et al. Among authors: o brien jp. Nature. 2021 Sep;597(7876):430-434. doi: 10.1038/s41586-021-03857-w. Epub 2021 Sep 1. Nature. 2021. PMID: 34471289 Free PMC article.
Electric field stimulates production of highly conductive microbial OmcZ nanowires.
Yalcin SE, O'Brien JP, Gu Y, Reiss K, Yi SM, Jain R, Srikanth V, Dahl PJ, Huynh W, Vu D, Acharya A, Chaudhuri S, Varga T, Batista VS, Malvankar NS. Yalcin SE, et al. Among authors: o brien jp. Nat Chem Biol. 2020 Oct;16(10):1136-1142. doi: 10.1038/s41589-020-0623-9. Epub 2020 Aug 17. Nat Chem Biol. 2020. PMID: 32807967 Free PMC article.
283 results