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AntimiR targeting of microRNA-134 reduces seizures in a mouse model of Angelman syndrome.
Campbell A, Morris G, Sanfeliu A, Augusto J, Langa E, Kesavan JC, Nguyen NT, Conroy RM, Worm J, Kielpinski L, Jensen MA, Miller MT, Kremer T, Reschke CR, Henshall DC. Campbell A, et al. Among authors: sanfeliu a. Mol Ther Nucleic Acids. 2022 Apr 20;28:514-529. doi: 10.1016/j.omtn.2022.04.009. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35592499 Free PMC article.
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, Freiman TM, Mahesh A, Tiwari VK, Rosenow F, Bauer S, Kjems J, Morris G, Henshall DC. Heiland M, et al. Among authors: sanfeliu a. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2216658120. doi: 10.1073/pnas.2216658120. Epub 2023 Jul 18. Proc Natl Acad Sci U S A. 2023. PMID: 37463203 Free PMC article.
Impact of JQ1 treatment on seizures, hippocampal gene expression, and gliosis in a mouse model of temporal lobe epilepsy.
Harnett A, Mathoux J, Wilson MM, Heiland M, Mamad O, Srinivas S, Sanfeliu A, Sanz-Rodriguez A, How KLE, Delanty N, Cryan J, Brett FM, Farrell MA, O'Brien DF, Henshall DC, Brennan GP. Harnett A, et al. Among authors: sanfeliu a. Eur J Neurosci. 2024 Sep;60(6):5266-5283. doi: 10.1111/ejn.16499. Epub 2024 Aug 16. Eur J Neurosci. 2024. PMID: 39149798
Excellent response to anti-CD38 therapy with daratumumab in a patient with severe refractory CANOMAD.
Pascual-Goñi E, Collet R, Tejada-Illa C, Martín-Aguilar L, Caballero-Ávila M, Lleixà C, Novelli S, López-Pardo J, Sanfeliu AE, Mariscal A, Álvaro Gargallo Y, Martínez-Hernández E, Cocho D, Querol L. Pascual-Goñi E, et al. Among authors: sanfeliu ae. J Neurol Neurosurg Psychiatry. 2024 Jun 17;95(7):609-611. doi: 10.1136/jnnp-2023-332443. J Neurol Neurosurg Psychiatry. 2024. PMID: 38341197
26 results