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Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.
Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, Valle LD, Trillo-Tinoco J, Maj T, Zou W, Rodriguez PC, Ochoa AC. Hossain F, et al. Among authors: rodriguez pc. Cancer Immunol Res. 2015 Nov;3(11):1236-47. doi: 10.1158/2326-6066.CIR-15-0036. Epub 2015 May 29. Cancer Immunol Res. 2015. PMID: 26025381 Free PMC article.
Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance.
Sierra RA, Trillo-Tinoco J, Mohamed E, Yu L, Achyut BR, Arbab A, Bradford JW, Osborne BA, Miele L, Rodriguez PC. Sierra RA, et al. Among authors: rodriguez pc. Cancer Res. 2017 Oct 15;77(20):5628-5638. doi: 10.1158/0008-5472.CAN-17-0357. Epub 2017 Sep 13. Cancer Res. 2017. PMID: 28904063 Free PMC article.
Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.
Hossain F, Majumder S, Ucar DA, Rodriguez PC, Golde TE, Minter LM, Osborne BA, Miele L. Hossain F, et al. Among authors: rodriguez pc. Front Immunol. 2018 Jun 4;9:1288. doi: 10.3389/fimmu.2018.01288. eCollection 2018. Front Immunol. 2018. PMID: 29915603 Free PMC article. Review.
AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells.
Trillo-Tinoco J, Sierra RA, Mohamed E, Cao Y, de Mingo-Pulido Á, Gilvary DL, Anadon CM, Costich TL, Wei S, Flores ER, Ruffell B, Conejo-Garcia JR, Rodriguez PC. Trillo-Tinoco J, et al. Among authors: rodriguez pc. Cancer Res. 2019 Oct 1;79(19):5034-5047. doi: 10.1158/0008-5472.CAN-19-0880. Epub 2019 Aug 13. Cancer Res. 2019. PMID: 31409640 Free PMC article.
The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling.
Mohamed E, Sierra RA, Trillo-Tinoco J, Cao Y, Innamarato P, Payne KK, de Mingo Pulido A, Mandula J, Zhang S, Thevenot P, Biswas S, Abdalla SK, Costich TL, Hänggi K, Anadon CM, Flores ER, Haura EB, Mehrotra S, Pilon-Thomas S, Ruffell B, Munn DH, Cubillos-Ruiz JR, Conejo-Garcia JR, Rodriguez PC. Mohamed E, et al. Among authors: rodriguez pc. Immunity. 2020 Apr 14;52(4):668-682.e7. doi: 10.1016/j.immuni.2020.03.004. Immunity. 2020. PMID: 32294407 Free PMC article.
Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma.
Jain MD, Zhao H, Wang X, Atkins R, Menges M, Reid K, Spitler K, Faramand R, Bachmeier C, Dean EA, Cao B, Chavez JC, Shah B, Lazaryan A, Nishihori T, Hussaini M, Gonzalez RJ, Mullinax JE, Rodriguez PC, Conejo-Garcia JR, Anasetti C, Davila ML, Locke FL. Jain MD, et al. Among authors: rodriguez pc. Blood. 2021 May 13;137(19):2621-2633. doi: 10.1182/blood.2020007445. Blood. 2021. PMID: 33512407 Free PMC article.
Tumor-related stress regulates functional plasticity of MDSCs.
Mandula JK, Rodriguez PC. Mandula JK, et al. Among authors: rodriguez pc. Cell Immunol. 2021 May;363:104312. doi: 10.1016/j.cellimm.2021.104312. Epub 2021 Feb 12. Cell Immunol. 2021. PMID: 33652258 Free PMC article. Review.
Innate immune cells in the tumor microenvironment.
Li MO, Wolf N, Raulet DH, Akkari L, Pittet MJ, Rodriguez PC, Kaplan RN, Munitz A, Zhang Z, Cheng S, Bhardwaj N. Li MO, et al. Among authors: rodriguez pc. Cancer Cell. 2021 Jun 14;39(6):725-729. doi: 10.1016/j.ccell.2021.05.016. Cancer Cell. 2021. PMID: 34129817 Free article.
157 results