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Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance.
Yin K, Patten D, Gough S, de Barros Gonçalves S, Chan A, Olan I, Cassidy L, Poblocka M, Zhu H, Lun A, Schuijs M, Young A, Martinez-Jimenez C, Halim TYF, Shetty S, Narita M, Hoare M. Yin K, et al. Among authors: schuijs m. Genes Dev. 2022 May 1;36(9-10):533-549. doi: 10.1101/gad.349585.122. Epub 2022 May 26. Genes Dev. 2022. PMID: 35618311 Free PMC article.
BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis.
Imianowski CJ, Whiteside SK, Lozano T, Evans AC, Benson JD, Courreges CJF, Sadiyah F, Lau CM, Zandhuis ND, Grant FM, Schuijs MJ, Vardaka P, Kuo P, Soilleux EJ, Yang J, Sun JC, Kurosaki T, Okkenhaug K, Halim TYF, Roychoudhuri R. Imianowski CJ, et al. Among authors: schuijs mj. J Exp Med. 2022 Dec 5;219(12):e20211476. doi: 10.1084/jem.20211476. Epub 2022 Sep 30. J Exp Med. 2022. PMID: 36178457 Free PMC article.
Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia.
Petruzzelli M, Ferrer M, Schuijs MJ, Kleeman SO, Mourikis N, Hall Z, Perera D, Raghunathan S, Vacca M, Gaude E, Lukey MJ, Jodrell DI, Frezza C, Wagner EF, Venkitaraman AR, Halim TYF, Janowitz T. Petruzzelli M, et al. Among authors: schuijs mj. Cancers (Basel). 2022 Feb 15;14(4):963. doi: 10.3390/cancers14040963. Cancers (Basel). 2022. PMID: 35205709 Free PMC article.
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Schuijs MJ, Png S, Richard AC, Tsyben A, Hamm G, Stockis J, Garcia C, Pinaud S, Nicholls A, Ros XR, Su J, Eldridge MD, Riedel A, Serrao EM, Rodewald HR, Mack M, Shields JD, Cohen ES, McKenzie ANJ, Goodwin RJA, Brindle KM, Marioni JC, Halim TYF. Schuijs MJ, et al. Nat Immunol. 2020 Sep;21(9):998-1009. doi: 10.1038/s41590-020-0745-y. Epub 2020 Aug 3. Nat Immunol. 2020. PMID: 32747815 Free PMC article.
IL-33trap is a novel IL-33-neutralizing biologic that inhibits allergic airway inflammation.
Holgado A, Braun H, Van Nuffel E, Detry S, Schuijs MJ, Deswarte K, Vergote K, Haegman M, Baudelet G, Haustraete J, Hammad H, Lambrecht BN, Savvides SN, Afonina IS, Beyaert R. Holgado A, et al. Among authors: schuijs mj. J Allergy Clin Immunol. 2019 Jul;144(1):204-215. doi: 10.1016/j.jaci.2019.02.028. Epub 2019 Mar 13. J Allergy Clin Immunol. 2019. PMID: 30876911 Free PMC article.
TNF-α-induced protein 3 levels in lung dendritic cells instruct TH2 or TH17 cell differentiation in eosinophilic or neutrophilic asthma.
Vroman H, Bergen IM, van Hulst JAC, van Nimwegen M, van Uden D, Schuijs MJ, Pillai SY, van Loo G, Hammad H, Lambrecht BN, Hendriks RW, Kool M. Vroman H, et al. Among authors: schuijs mj. J Allergy Clin Immunol. 2018 May;141(5):1620-1633.e12. doi: 10.1016/j.jaci.2017.08.012. Epub 2017 Sep 6. J Allergy Clin Immunol. 2018. PMID: 28888782
A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection.
Maelfait J, Roose K, Vereecke L, Mc Guire C, Sze M, Schuijs MJ, Willart M, Ibañez LI, Hammad H, Lambrecht BN, Beyaert R, Saelens X, van Loo G. Maelfait J, et al. Among authors: schuijs mj. PLoS Pathog. 2016 Jan 27;12(1):e1005410. doi: 10.1371/journal.ppat.1005410. eCollection 2016 Jan. PLoS Pathog. 2016. PMID: 26815999 Free PMC article.
32 results