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Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth.
Cao M, Isaac R, Yan W, Ruan X, Jiang L, Wan Y, Wang J, Wang E, Caron C, Neben S, Drygin D, Pizzo DP, Wu X, Liu X, Chin AR, Fong MY, Gao Z, Guo K, Fadare O, Schwab RB, Yuan Y, Yost SE, Mortimer J, Zhong W, Ying W, Bui JD, Sears DD, Olefsky JM, Wang SE. Cao M, et al. Among authors: olefsky jm. Nat Cell Biol. 2022 Jun;24(6):954-967. doi: 10.1038/s41556-022-00919-7. Epub 2022 May 30. Nat Cell Biol. 2022. PMID: 35637408 Free PMC article.
Impaired insulin secretion in a mouse model of ataxia telangiectasia.
Miles PD, Treuner K, Latronica M, Olefsky JM, Barlow C. Miles PD, et al. Among authors: olefsky jm. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E70-4. doi: 10.1152/ajpendo.00259.2006. Epub 2007 Mar 13. Am J Physiol Endocrinol Metab. 2007. PMID: 17356010 Free article.
Fat talks, liver and muscle listen.
Olefsky JM. Olefsky JM. Cell. 2008 Sep 19;134(6):914-6. doi: 10.1016/j.cell.2008.09.001. Cell. 2008. PMID: 18805083 Free article.
PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization.
Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, Evans RM. Sugii S, et al. Among authors: olefsky jm. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22504-9. doi: 10.1073/pnas.0912487106. Epub 2009 Dec 16. Proc Natl Acad Sci U S A. 2009. PMID: 20018750 Free PMC article.
Fat-induced inflammation unchecked.
Osborn O, Sears DD, Olefsky JM. Osborn O, et al. Among authors: olefsky jm. Cell Metab. 2010 Dec 1;12(6):553-4. doi: 10.1016/j.cmet.2010.11.017. Cell Metab. 2010. PMID: 21109185 Free article.
546 results