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Page 1
Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure.
De Genst E, Foo KS, Xiao Y, Rohner E, de Vries E, Sohlmér J, Witman N, Hidalgo A, Kolstad TRS, Louch WE, Pehrsson S, Park A, Ikeda Y, Li X, Mayr LM, Wickson K, Jennbacken K, Hansson K, Fritsche-Danielson R, Hunt J, Chien KR. De Genst E, et al. Among authors: de vries e. Nat Commun. 2022 May 31;13(1):3018. doi: 10.1038/s41467-022-29703-9. Nat Commun. 2022. PMID: 35641497 Free PMC article.
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation.
Fletcher A, Clift D, de Vries E, Martinez Cuesta S, Malcolm T, Meghini F, Chaerkady R, Wang J, Chiang A, Weng SHS, Tart J, Wong E, Donohoe G, Rawlins P, Gordon E, Taylor JD, James L, Hunt J. Fletcher A, et al. Among authors: de vries e. Nat Commun. 2023 Nov 4;14(1):7093. doi: 10.1038/s41467-023-42546-2. Nat Commun. 2023. PMID: 37925433 Free PMC article.
Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).
Bellos E, Santillo D, Vantourout P, Jackson HR, Duret A, Hearn H, Seeleuthner Y, Talouarn E, Hodeib S, Patel H, Powell O, Yeoh S, Mustafa S, Habgood-Coote D, Nichols S, Estramiana Elorrieta L, D'Souza G, Wright VJ, Estrada-Rivadeneyra D, Tremoulet AH, Dummer KB, Netea SA, Condino-Neto A, Lau YL, Núñez Cuadros E, Toubiana J, Holanda Pena M, Rieux-Laucat F, Luyt CE, Haerynck F, Mège JL, Chakravorty S, Haddad E, Morin MP, Metin Akcan Ö, Keles S, Emiroglu M, Alkan G, Tüter Öz SK, Elmas Bozdemir S, Morelle G, Volokha A, Kendir-Demirkol Y, Sözeri B, Coskuner T, Yahsi A, Gulhan B, Kanik-Yuksek S, Bayhan GI, Ozkaya-Parlakay A, Yesilbas O, Hatipoglu N, Ozcelik T, Belot A, Chopin E, Barlogis V, Sevketoglu E, Menentoglu E, Gayretli Aydin ZG, Bloomfield M, AlKhater SA, Cyrus C, Stepanovskiy Y, Bondarenko A, Öz FN, Polat M, Fremuth J, Lebl J, Geraldo A, Jouanguy E; COVID-19 Human Genetic Effort; DIAMONDS; EUCLIDS; Carter MJ, Wellman P, Peters M, Pérez de Diego R, Edwards LA, Chiu C, Noursadeghi M, Bolze A, Shimizu C, Kaforou M, Hamilton MS, Herberg JA, Schmitt EG, Rodriguez-Palmero A, Pujol A, Kim J, Cobat A, Abel L, Zhang SY, Casanova JL, Kuijpers TW, Burns JC, Levin M, Hayday AC, Sancho-Shim… See abstract for full author list ➔ Bellos E, et al. J Exp Med. 2024 Dec 2;221(12):e920240699. doi: 10.1084/jem.20240699. Epub 2024 Nov 22. J Exp Med. 2024. PMID: 39576310
Long-Term Outcomes of Early Surgery vs Endoscopy First in Chronic Pancreatitis: Follow-Up Analysis of the ESCAPE Randomized Clinical Trial.
van Veldhuisen CL, Kempeneers MA, de Rijk FEM, Bouwense SA, Bruno MJ, Fockens P, Poley JW, Ali UA, Bollen TL, Busch OR, van Duijvendijk P, van Dullemen HM, van Eijck CH, Van Goor H, Hadithi M, Haveman JW, Keulemans Y, Nieuwenhuijs VB, Poen AC, Voermans RP, Tan AC, Thijs W, Verdonk RC, Witteman BJ, van Hooft JE, van Santvoort HC, Dijkgraaf MG, Besselink MG, Boermeester MA, Issa Y; Dutch Pancreatitis Study Group. van Veldhuisen CL, et al. JAMA Surg. 2024 Nov 20:e245182. doi: 10.1001/jamasurg.2024.5182. Online ahead of print. JAMA Surg. 2024. PMID: 39565607 Free PMC article.
Increased dopamine D2/D3 receptor and serotonin transporter availability in male rats after spontaneous remission from repeated social defeat-induced depression; a PET study in rats.
Moraga-Amaro R, Vazquez-Matias DA, Nazario LR, Dierckx RAJO, Stehberg J, Doorduin J, de Vries EFJ. Moraga-Amaro R, et al. Among authors: de vries efj. Neurobiol Dis. 2024 Nov;202:106727. doi: 10.1016/j.nbd.2024.106727. Epub 2024 Nov 6. Neurobiol Dis. 2024. PMID: 39515530 Free article.
Integrating molecular imaging and transcriptomic profiling in advanced HER2-positive breast cancer receiving trastuzumab emtansine (T-DM1): an analysis of the ZEPHIR clinical trial.
Rediti M, Fimereli D, Mileva M, Wimana Z, Venet D, Flamen P, Guiot T, de Vries EGE, Schröder CP, Menke-van der Houven van Oordt CW, Maetens M, Majjaj S, Larsimont D, Rothé F, Sotiriou C, Gebhart G. Rediti M, et al. Among authors: de vries ege. Clin Cancer Res. 2024 Oct 29. doi: 10.1158/1078-0432.CCR-24-1007. Online ahead of print. Clin Cancer Res. 2024. PMID: 39470686
Trastuzumab Duocarmazine in Pretreated Human Epidermal Growth Factor Receptor 2-Positive Advanced or Metastatic Breast Cancer: An Open-Label, Randomized, Phase III Trial (TULIP).
Turner N, Saura C, Aftimos P, van den Tweel E, Oesterholt M, Koper N, Colleoni M, Kaczmarek E, Punie K, Song X, Armstrong A, Bianchi G, Stradella A, Ladoire S, Lim JSJ, Quenel-Tueux N, Tan TJ, Escrivá-de-Romaní S, O'Shaughnessy J; TULIP Trial Investigators. Turner N, et al. J Clin Oncol. 2024 Oct 23:JCO2400529. doi: 10.1200/JCO.24.00529. Online ahead of print. J Clin Oncol. 2024. PMID: 39442070
2,023 results