Chu VT - Search Results

1

Precise CRISPR-Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.

Tran NT, Danner E, Li X, Graf R, Lebedin M, de la Rosa K, Kühn R, Rajewsky K, Chu VT. Tran NT, et al. Among authors: chu vt. Sci Adv. 2022 Jun 3;8(22):eabm9106. doi: 10.1126/sciadv.abm9106. Epub 2022 Jun 3. Sci Adv. 2022. PMID: 35658035 Free PMC article.

2

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

Chu VT, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, Kühn R. Chu VT, et al. Nat Biotechnol. 2015 May;33(5):543-8. doi: 10.1038/nbt.3198. Epub 2015 Mar 24. Nat Biotechnol. 2015. PMID: 25803306

3

Pop in, pop out: a novel gene-targeting strategy for use with CRISPR-Cas9.

Kühn R, Chu VT. Kühn R, et al. Among authors: chu vt. Genome Biol. 2015 Nov 10;16:244. doi: 10.1186/s13059-015-0810-2. Genome Biol. 2015. PMID: 26553112 Free PMC article.

4

PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones.

Sander S, Chu VT, Yasuda T, Franklin A, Graf R, Calado DP, Li S, Imami K, Selbach M, Di Virgilio M, Bullinger L, Rajewsky K. Sander S, et al. Among authors: chu vt. Immunity. 2015 Dec 15;43(6):1075-86. doi: 10.1016/j.immuni.2015.10.021. Epub 2015 Nov 24. Immunity. 2015. PMID: 26620760 Free article.

5

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.

Chu VT, Weber T, Graf R, Sommermann T, Petsch K, Sack U, Volchkov P, Rajewsky K, Kühn R. Chu VT, et al. BMC Biotechnol. 2016 Jan 16;16:4. doi: 10.1186/s12896-016-0234-4. BMC Biotechnol. 2016. PMID: 26772810 Free PMC article.

6

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.

Chu VT, Graf R, Wirtz T, Weber T, Favret J, Li X, Petsch K, Tran NT, Sieweke MH, Berek C, Kühn R, Rajewsky K. Chu VT, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12514-12519. doi: 10.1073/pnas.1613884113. Epub 2016 Oct 11. Proc Natl Acad Sci U S A. 2016. PMID: 27729526 Free PMC article.

7

CRISPR/Cas9-Mediated In Vitro Mutagenesis in GC-Like B Cells.

Chu VT, Graf R, Rajewsky K. Chu VT, et al. Methods Mol Biol. 2017;1623:135-145. doi: 10.1007/978-1-4939-7095-7_12. Methods Mol Biol. 2017. PMID: 28589354

8

Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells.

Kabrani E, Chu VT, Tasouri E, Sommermann T, Baßler K, Ulas T, Zenz T, Bullinger L, Schultze JL, Rajewsky K, Sander S. Kabrani E, et al. Among authors: chu vt. Blood. 2018 Dec 20;132(25):2670-2683. doi: 10.1182/blood-2018-06-856203. Epub 2018 Oct 17. Blood. 2018. PMID: 30333121 Free article.

9

A novel allele for inducible Cre expression in germinal center B cells.

Weber T, Seagal J, Winkler W, Wirtz T, Chu VT, Rajewsky K. Weber T, et al. Among authors: chu vt. Eur J Immunol. 2019 Jan;49(1):192-194. doi: 10.1002/eji.201847863. Epub 2018 Nov 20. Eur J Immunol. 2019. PMID: 30359469 Free article.

10

sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing.

Graf R, Li X, Chu VT, Rajewsky K. Graf R, et al. Among authors: chu vt. Cell Rep. 2019 Jan 29;26(5):1098-1103.e3. doi: 10.1016/j.celrep.2019.01.024. Cell Rep. 2019. PMID: 30699341 Free PMC article.

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