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TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response.
Kim T, Johnston J, Castillo-Lluva S, Cimas FJ, Hamby S; Cardiogenics Consortium*; Gonzalez-Moreno S, Villarejo-Campos P, Goodall AH, Velasco G, Ocana A, Muthana M, Kiss-Toth E. Kim T, et al. Theranostics. 2022 Apr 24;12(8):3584-3600. doi: 10.7150/thno.72192. eCollection 2022. Theranostics. 2022. PMID: 35664073 Free PMC article.
The Pseudokinase TRIB3 Negatively Regulates the HER2 Receptor Pathway and Is a Biomarker of Good Prognosis in Luminal Breast Cancer.
Orea-Soufi A, Castillo-Lluva S, Salvador-Tormo N, Martín-Cabrera P, Recuero S, Gabicagogeascoa E, Moreno-Valladares M, Mendiburu-Eliçabe M, Blanco-Gómez A, Ramos-Pittol JM, García-Taboada E, Ocaña A, Cimas FJ, Matheu A, Álvarez-López I, Velasco G, Lorente M. Orea-Soufi A, et al. Cancers (Basel). 2021 Oct 22;13(21):5307. doi: 10.3390/cancers13215307. Cancers (Basel). 2021. PMID: 34771470 Free PMC article.
POTEE promotes breast cancer cell malignancy by inducing invadopodia formation through the activation of SUMOylated Rac1.
Martínez-López A, García-Casas A, Infante G, González-Fernández M, Salvador N, Lorente M, Mendiburu-Eliçabe M, Gonzalez-Moreno S, Villarejo-Campos P, Velasco G, Malliri A, Castillo-Lluva S. Martínez-López A, et al. Among authors: castillo lluva s. Mol Oncol. 2024 Mar;18(3):620-640. doi: 10.1002/1878-0261.13568. Epub 2023 Dec 27. Mol Oncol. 2024. PMID: 38098337 Free PMC article.
A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.
Castillo-Lluva S, Hontecillas-Prieto L, Blanco-Gómez A, Del Mar Sáez-Freire M, García-Cenador B, García-Criado J, Pérez-Andrés M, Orfao A, Cañamero M, Mao JH, Gridley T, Castellanos-Martín A, Pérez-Losada J. Castillo-Lluva S, et al. Oncogene. 2015 Sep 3;34(36):4777-90. doi: 10.1038/onc.2015.224. Epub 2015 Jun 22. Oncogene. 2015. PMID: 26096931 Free PMC article.
Stromal SNAI2 Is Required for ERBB2 Breast Cancer Progression.
Blanco-Gómez A, Hontecillas-Prieto L, Corchado-Cobos R, García-Sancha N, Salvador N, Castellanos-Martín A, Sáez-Freire MDM, Mendiburu-Eliçabe M, Alonso-López D, De Las Rivas J, Lorente M, García-Casas A, Del Carmen S, Abad-Hernández MDM, Cruz-Hernández JJ, Rodríguez-Sánchez CA, Claros-Ampuero J, García-Cenador B, García-Criado J, Orimo A, Gridley T, Pérez-Losada J, Castillo-Lluva S. Blanco-Gómez A, et al. Cancer Res. 2020 Dec 1;80(23):5216-5230. doi: 10.1158/0008-5472.CAN-20-0278. Epub 2020 Oct 6. Cancer Res. 2020. PMID: 33023950 Free PMC article.
Evolutionary Origins of Metabolic Reprogramming in Cancer.
García-Sancha N, Corchado-Cobos R, Gómez-Vecino A, Jiménez-Navas A, Pérez-Baena MJ, Blanco-Gómez A, Holgado-Madruga M, Mao JH, Cañueto J, Castillo-Lluva S, Mendiburu-Eliçabe M, Pérez-Losada J. García-Sancha N, et al. Int J Mol Sci. 2022 Oct 11;23(20):12063. doi: 10.3390/ijms232012063. Int J Mol Sci. 2022. PMID: 36292921 Free PMC article. Review.
SUMOylation regulates the aggressiveness of breast cancer-associated fibroblasts.
Martínez-López A, Infante G, Mendiburu-Eliçabe M, Machuca A, Antón OM, González-Fernández M, Luque-García JL, Clarke RB, Castillo-Lluva S. Martínez-López A, et al. Among authors: castillo lluva s. Cell Oncol (Dordr). 2024 Oct 21. doi: 10.1007/s13402-024-01005-w. Online ahead of print. Cell Oncol (Dordr). 2024. PMID: 39432155
Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer.
Andradas C, Blasco-Benito S, Castillo-Lluva S, Dillenburg-Pilla P, Diez-Alarcia R, Juanes-García A, García-Taboada E, Hernando-Llorente R, Soriano J, Hamann S, Wenners A, Alkatout I, Klapper W, Rocken C, Bauer M, Arnold N, Quintanilla M, Megías D, Vicente-Manzanares M, Urigüen L, Gutkind JS, Guzmán M, Pérez-Gómez E, Sánchez C. Andradas C, et al. Oncotarget. 2016 Jul 26;7(30):47565-47575. doi: 10.18632/oncotarget.10206. Oncotarget. 2016. PMID: 27340777 Free PMC article.
39 results