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Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
Pöhner I, Quotadamo A, Panecka-Hofman J, Luciani R, Santucci M, Linciano P, Landi G, Di Pisa F, Dello Iacono L, Pozzi C, Mangani S, Gul S, Witt G, Ellinger B, Kuzikov M, Santarem N, Cordeiro-da-Silva A, Costi MP, Venturelli A, Wade RC. Pöhner I, et al. Among authors: venturelli a. J Med Chem. 2022 Jul 14;65(13):9011-9033. doi: 10.1021/acs.jmedchem.2c00232. Epub 2022 Jun 8. J Med Chem. 2022. PMID: 35675511 Free PMC article.
Structure-based studies on species-specific inhibition of thymidylate synthase.
Costi MP, Tondi D, Rinaldi M, Barlocco D, Pecorari P, Soragni F, Venturelli A, Stroud RM. Costi MP, et al. Among authors: venturelli a. Biochim Biophys Acta. 2002 Jul 18;1587(2-3):206-14. doi: 10.1016/s0925-4439(02)00083-2. Biochim Biophys Acta. 2002. PMID: 12084462 Free article. Review.
New thymidylate synthase inhibitors induce apoptosis in melanoma cell lines.
Giudice S, Benassi L, Bertazzoni G, Costi MP, Gelain A, Venturelli A, Bernardi C, Gualdi G, Coppi A, Rossi T, Giannetti A, Magnoni C. Giudice S, et al. Among authors: venturelli a. Toxicol In Vitro. 2007 Mar;21(2):240-8. doi: 10.1016/j.tiv.2006.09.023. Epub 2006 Oct 6. Toxicol In Vitro. 2007. PMID: 17118621
63 results