Wen XH - Search Results

1

Adeno-Associated Virus Serotype 2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two-Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial.

Aleman TS, Huckfeldt RM, Serrano LW, Pearson DJ, Vergilio GK, McCague S, Marshall KA, Ashtari M, Doan TM, Weigel-DiFranco CA, Biron BS, Wen XH, Chung DC, Liu E, Ferenchak K, Morgan JIW, Pierce EA, Eliott D, Bennett J, Comander J, Maguire AM. Aleman TS, et al. Among authors: wen xh. Ophthalmology. 2022 Oct;129(10):1177-1191. doi: 10.1016/j.ophtha.2022.06.006. Epub 2022 Jun 15. Ophthalmology. 2022. PMID: 35714735 Clinical Trial.

2

Effects of low AIPL1 expression on phototransduction in rods.

Makino CL, Wen XH, Michaud N, Peshenko IV, Pawlyk B, Brush RS, Soloviev M, Liu X, Woodruff ML, Calvert PD, Savchenko AB, Anderson RE, Fain GL, Li T, Sandberg MA, Dizhoor AM. Makino CL, et al. Among authors: wen xh. Invest Ophthalmol Vis Sci. 2006 May;47(5):2185-94. doi: 10.1167/iovs.05-1341. Invest Ophthalmol Vis Sci. 2006. PMID: 16639031

3

Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics.

Makino CL, Wen XH, Michaud NA, Covington HI, DiBenedetto E, Hamm HE, Lem J, Caruso G. Makino CL, et al. Among authors: wen xh. PLoS One. 2012;7(5):e37832. doi: 10.1371/journal.pone.0037832. Epub 2012 May 25. PLoS One. 2012. PMID: 22662234 Free PMC article.

4

A role for GCAP2 in regulating the photoresponse. Guanylyl cyclase activation and rod electrophysiology in GUCA1B knock-out mice.

Makino CL, Peshenko IV, Wen XH, Olshevskaya EV, Barrett R, Dizhoor AM. Makino CL, et al. Among authors: wen xh. J Biol Chem. 2008 Oct 24;283(43):29135-43. doi: 10.1074/jbc.M804445200. Epub 2008 Aug 22. J Biol Chem. 2008. PMID: 18723510 Free PMC article.

5

Enzymatic relay mechanism stimulates cyclic GMP synthesis in rod photoresponse: biochemical and physiological study in guanylyl cyclase activating protein 1 knockout mice.

Makino CL, Wen XH, Olshevskaya EV, Peshenko IV, Savchenko AB, Dizhoor AM. Makino CL, et al. Among authors: wen xh. PLoS One. 2012;7(10):e47637. doi: 10.1371/journal.pone.0047637. Epub 2012 Oct 17. PLoS One. 2012. PMID: 23082185 Free PMC article.

6

Overexpression of rhodopsin alters the structure and photoresponse of rod photoreceptors.

Wen XH, Shen L, Brush RS, Michaud N, Al-Ubaidi MR, Gurevich VV, Hamm HE, Lem J, Dibenedetto E, Anderson RE, Makino CL. Wen XH, et al. Biophys J. 2009 Feb;96(3):939-50. doi: 10.1016/j.bpj.2008.10.016. Biophys J. 2009. PMID: 19186132 Free PMC article.

7

S100B serves as a Ca(2+) sensor for ROS-GC1 guanylate cyclase in cones but not in rods of the murine retina.

Wen XH, Duda T, Pertzev A, Venkataraman V, Makino CL, Sharma RK. Wen XH, et al. Cell Physiol Biochem. 2012;29(3-4):417-30. doi: 10.1159/000338496. Epub 2012 Apr 3. Cell Physiol Biochem. 2012. PMID: 22508049 Free PMC article.

8

Bicarbonate Modulates Photoreceptor Guanylate Cyclase (ROS-GC) Catalytic Activity.

Duda T, Wen XH, Isayama T, Sharma RK, Makino CL. Duda T, et al. Among authors: wen xh. J Biol Chem. 2015 Apr 24;290(17):11052-60. doi: 10.1074/jbc.M115.650408. Epub 2015 Mar 12. J Biol Chem. 2015. PMID: 25767116 Free PMC article.

9

AIPL1, the protein that is defective in Leber congenital amaurosis, is essential for the biosynthesis of retinal rod cGMP phosphodiesterase.

Liu X, Bulgakov OV, Wen XH, Woodruff ML, Pawlyk B, Yang J, Fain GL, Sandberg MA, Makino CL, Li T. Liu X, et al. Among authors: wen xh. Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13903-8. doi: 10.1073/pnas.0405160101. Epub 2004 Sep 13. Proc Natl Acad Sci U S A. 2004. PMID: 15365173 Free PMC article.

10

Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals.

Yang J, Pawlyk B, Wen XH, Adamian M, Soloviev M, Michaud N, Zhao Y, Sandberg MA, Makino CL, Li T. Yang J, et al. Among authors: wen xh. Hum Mol Genet. 2007 May 1;16(9):1017-29. doi: 10.1093/hmg/ddm047. Epub 2007 Mar 6. Hum Mol Genet. 2007. PMID: 17341488

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