Liang Y - Search Results

1

Natural medicine HLXL targets multiple pathways of amyloid-mediated neuroinflammation and immune response in treating alzheimer's disease.

Liang Y, Lee DYW, Zhen S, Sun H, Zhu B, Liu J, Lei D, Lin CJ, Zhang S, Jacques NA, Quinti L, Ran C, Wang C, Griciuc A, Choi SH, Dai RH, Efferth T, Tanzi RE, Zhang C. Liang Y, et al. Phytomedicine. 2022 Sep;104:154158. doi: 10.1016/j.phymed.2022.154158. Epub 2022 May 13. Phytomedicine. 2022. PMID: 35728383

2

Upregulation of Alzheimer's Disease Amyloid-β Protein Precursor in Astrocytes Both in vitro and in vivo.

Liang Y, Raven F, Ward JF, Zhen S, Zhang S, Sun H, Miller SJ, Choi SH, Tanzi RE, Zhang C. Liang Y, et al. J Alzheimers Dis. 2020;76(3):1071-1082. doi: 10.3233/JAD-200128. J Alzheimers Dis. 2020. PMID: 32597805 Free PMC article.

3

Degradation and inhibition of epigenetic regulatory protein BRD4 exacerbate Alzheimer's disease-related neuropathology in cell models.

Zhang S, Bai P, Lei D, Liang Y, Zhen S, Bakiasi G, Pang H, Choi SH, Wang C, Tanzi RE, Zhang C. Zhang S, et al. Among authors: liang y. J Biol Chem. 2022 Apr;298(4):101794. doi: 10.1016/j.jbc.2022.101794. Epub 2022 Mar 3. J Biol Chem. 2022. PMID: 35248531 Free PMC article.

4

A Curcumin Analog Reduces Levels of the Alzheimer's Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy.

Wan Y, Liang Y, Liang F, Shen N, Shinozuka K, Yu JT, Ran C, Quan Q, Tanzi RE, Zhang C. Wan Y, et al. Among authors: liang f, liang y. J Alzheimers Dis. 2019;72(3):761-771. doi: 10.3233/JAD-190562. J Alzheimers Dis. 2019. PMID: 31640096

5

Negative evidence for a role of APH1B T27I variant in Alzheimer's disease.

Zhang X, Zhang C, Prokopenko D, Liang Y, Han W, Tanzi RE, Sisodia SS. Zhang X, et al. Among authors: liang y. Hum Mol Genet. 2020 Apr 15;29(6):955-966. doi: 10.1093/hmg/ddaa017. Hum Mol Genet. 2020. PMID: 31995180

6

Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates.

Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C. Xu Y, et al. Among authors: liang y. J Exp Med. 2020 Dec 7;217(12):e20182266. doi: 10.1084/jem.20182266. J Exp Med. 2020. PMID: 32936886 Free PMC article.

7

An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo.

Zhang X, Zhang CM, Prokopenko D, Liang Y, Zhen SY, Weigle IQ, Han W, Aryal M, Tanzi RE, Sisodia SS. Zhang X, et al. Among authors: liang y. J Exp Med. 2021 Jun 7;218(6):e20210313. doi: 10.1084/jem.20210313. J Exp Med. 2021. PMID: 33822840 Free PMC article.

8

Molecular imaging of NAD⁺ -dependent deacetylase SIRT1 in the brain.

Xu Y, Chen Z, Wey HY, Liang Y, Tanzi RE, Zhang C, Wang C. Xu Y, et al. Among authors: liang y. Alzheimers Dement. 2021 Dec;17(12):1988-1997. doi: 10.1002/alz.12344. Epub 2021 Apr 15. Alzheimers Dement. 2021. PMID: 33860595

9

Significant Upregulation of Alzheimer's β-Amyloid Levels in a Living System Induced by Extracellular Elastin Polypeptides.

Ma C, Su J, Sun Y, Feng Y, Shen N, Li B, Liang Y, Yang X, Wu H, Zhang H, Herrmann A, Tanzi RE, Liu K, Zhang C. Ma C, et al. Among authors: liang y. Angew Chem Int Ed Engl. 2019 Dec 16;58(51):18703-18709. doi: 10.1002/anie.201912399. Epub 2019 Nov 4. Angew Chem Int Ed Engl. 2019. PMID: 31609093 Free PMC article. Review.

10

Epitope alteration by small molecules and applications in drug discovery.

Zhu B, Yang J, Van R, Yang F, Yu Y, Yu A, Ran K, Yin K, Liang Y, Shen X, Yin W, Choi SH, Lu Y, Wang C, Shao Y, Shi L, Tanzi RE, Zhang C, Cheng Y, Zhang Z, Ran C. Zhu B, et al. Among authors: liang y. Chem Sci. 2022 Jun 28;13(27):8104-8116. doi: 10.1039/d2sc02819k. eCollection 2022 Jul 13. Chem Sci. 2022. PMID: 35919434 Free PMC article.

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