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Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1.
Liu HC, Viswanath DI, Pesaresi F, Xu Y, Zhang L, Di Trani N, Paez-Mayorga J, Hernandez N, Wang Y, Erm DR, Ho J, Susnjar A, Liu X, Demaria S, Chen SH, Teh BS, Butler EB, Xuan Chua CY, Grattoni A. Liu HC, et al. Among authors: xu y. Int J Radiat Oncol Biol Phys. 2021 Jun 1;110(2):492-506. doi: 10.1016/j.ijrobp.2020.07.2326. Epub 2020 Aug 5. Int J Radiat Oncol Biol Phys. 2021. PMID: 32768562 Free PMC article.
Virus-Mimic mRNA Vaccine for Cancer Treatment.
Meng C, Chen Z, Mai J, Shi Q, Tian S, Hinkle L, Li J, Zhang Z, Ramirez M, Zhang L, Xu Y, Zhang J, Pan PY, Chen SH, Li H, Shen H. Meng C, et al. Among authors: xu y. Adv Ther (Weinh). 2021 Nov;4(11):2100144. doi: 10.1002/adtp.202100144. Epub 2021 Sep 17. Adv Ther (Weinh). 2021. PMID: 34901386 Free PMC article.
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer.
Chung AW, Anand K, Anselme AC, Chan AA, Gupta N, Venta LA, Schwartz MR, Qian W, Xu Y, Zhang L, Kuhn J, Patel T, Rodriguez AA, Belcheva A, Darcourt J, Ensor J, Bernicker E, Pan PY, Chen SH, Lee DJ, Niravath PA, Chang JC. Chung AW, et al. Among authors: xu y. Sci Transl Med. 2021 Dec 15;13(624):eabj5070. doi: 10.1126/scitranslmed.abj5070. Epub 2021 Dec 15. Sci Transl Med. 2021. PMID: 34910551 Clinical Trial.
Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome.
Jewell BE, Xu A, Zhu D, Huang MF, Lu L, Liu M, Underwood EL, Park JH, Fan H, Gingold JA, Zhou R, Tu J, Huo Z, Liu Y, Jin W, Chen YH, Xu Y, Chen SH, Rainusso N, Berg NK, Bazer DA, Vellano C, Jones P, Eltzschig HK, Zhao Z, Kaipparettu BA, Zhao R, Wang LL, Lee DF. Jewell BE, et al. Among authors: xu a, xu y. PLoS Genet. 2021 Dec 29;17(12):e1009971. doi: 10.1371/journal.pgen.1009971. eCollection 2021 Dec. PLoS Genet. 2021. PMID: 34965247 Free PMC article.
Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer.
Singh S, Lee N, Pedroza DA, Bado IL, Hamor C, Zhang L, Aguirre S, Hu J, Shen Y, Xu Y, Gao Y, Zhao N, Chen SH, Wan YW, Liu Z, Chang JT, Hollern D, Perou CM, Zhang XHF, Rosen JM. Singh S, et al. Among authors: xu y. Cancer Res. 2022 Jun 15;82(12):2281-2297. doi: 10.1158/0008-5472.CAN-21-3714. Cancer Res. 2022. PMID: 35442423 Free PMC article.
A Phase 2 Trial of Enhancing Immune Checkpoint Blockade by Stereotactic Radiation and In Situ Virus Gene Therapy in Metastatic Triple-Negative Breast Cancer.
Sun K, Xu Y, Zhang L, Niravath P, Darcourt J, Patel T, Teh BS, Farach AM, Guerrero C, Mathur S, Sultenfuss MA, Gupta N, Schwartz MR, Haley SL, Nair S, Li X, Nguyen TTA, Butner JD, Ensor J, Mejia JA, Mei Z, Butler EB, Chen SH, Bernicker EH, Chang JC. Sun K, et al. Among authors: xu y. Clin Cancer Res. 2022 Oct 14;28(20):4392-4401. doi: 10.1158/1078-0432.CCR-22-0622. Clin Cancer Res. 2022. PMID: 35877117 Free PMC article. Clinical Trial.
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