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Page 1
Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.
Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Kok M, Esserman LJ, van 't Veer LJ, Rugo HS, Curtis C, Klefström J, Matloubian M, Goga A. Lee JV, et al. Among authors: klefstrom j. Nat Commun. 2022 Jun 27;13(1):3671. doi: 10.1038/s41467-022-31238-y. Nat Commun. 2022. PMID: 35760778 Free PMC article.
MYC and AMPK-Save Energy or Die!
Haikala HM, Anttila JM, Klefström J. Haikala HM, et al. Among authors: klefstrom j. Front Cell Dev Biol. 2017 Apr 11;5:38. doi: 10.3389/fcell.2017.00038. eCollection 2017. Front Cell Dev Biol. 2017. PMID: 28443281 Free PMC article. Review.
Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J. Haikala HM, et al. Among authors: klefstrom j. Nat Commun. 2019 Feb 6;10(1):620. doi: 10.1038/s41467-019-08541-2. Nat Commun. 2019. PMID: 30728358 Free PMC article.
Publisher Correction: Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy.
Haikala HM, Anttila JM, Marques E, Raatikainen T, Ilander M, Hakanen H, Ala-Hongisto H, Savelius M, Balboa D, Von Eyss B, Eskelinen V, Munne P, Nieminen AI, Otonkoski T, Schüler J, Laajala TD, Aittokallio T, Sihto H, Mattson J, Heikkilä P, Leidenius M, Joensuu H, Mustjoki S, Kovanen P, Eilers M, Leverson JD, Klefström J. Haikala HM, et al. Among authors: klefstrom j. Nat Commun. 2019 Feb 20;10(1):932. doi: 10.1038/s41467-019-08956-x. Nat Commun. 2019. PMID: 30787321 Free PMC article.
Hepsin regulates TGFβ signaling via fibronectin proteolysis.
Belitškin D, Pant SM, Munne P, Suleymanova I, Belitškina K, Hongisto HA, Englund J, Raatikainen T, Klezovitch O, Vasioukhin V, Li S, Wu Q, Monni O, Kuure S, Laakkonen P, Pouwels J, Tervonen TA, Klefström J. Belitškin D, et al. Among authors: klefstrom j. EMBO Rep. 2021 Nov 4;22(11):e52532. doi: 10.15252/embr.202152532. Epub 2021 Sep 13. EMBO Rep. 2021. PMID: 34515392 Free PMC article.
Sortilin-related receptor is a druggable therapeutic target in breast cancer.
Al-Akhrass H, Pietilä M, Lilja J, Vesilahti EM, Anttila JM, Haikala HM, Munne PM, Klefström J, Peuhu E, Ivaska J. Al-Akhrass H, et al. Among authors: klefstrom j. Mol Oncol. 2022 Jan;16(1):116-129. doi: 10.1002/1878-0261.13106. Epub 2021 Oct 10. Mol Oncol. 2022. PMID: 34564954 Free PMC article.
Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer.
Munne PM, Martikainen L, Räty I, Bertula K, Nonappa, Ruuska J, Ala-Hongisto H, Peura A, Hollmann B, Euro L, Yavuz K, Patrikainen L, Salmela M, Pokki J, Kivento M, Väänänen J, Suomi T, Nevalaita L, Mutka M, Kovanen P, Leidenius M, Meretoja T, Hukkinen K, Monni O, Pouwels J, Sahu B, Mattson J, Joensuu H, Heikkilä P, Elo LL, Metcalfe C, Junttila MR, Ikkala O, Klefström J. Munne PM, et al. Among authors: klefstrom j. Nat Commun. 2021 Nov 29;12(1):6967. doi: 10.1038/s41467-021-27220-9. Nat Commun. 2021. PMID: 34845227 Free PMC article.
Strain-Stiffening of Agarose Gels.
Bertula K, Martikainen L, Munne P, Hietala S, Klefström J, Ikkala O, Nonappa. Bertula K, et al. Among authors: klefstrom j. ACS Macro Lett. 2019 Jun 18;8(6):670-675. doi: 10.1021/acsmacrolett.9b00258. Epub 2019 May 23. ACS Macro Lett. 2019. PMID: 35619522
Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.
Lee JV, Housley F, Yau C, Nakagawa R, Winkler J, Anttila JM, Munne PM, Savelius M, Houlahan KE, Van de Mark D, Hemmati G, Hernandez GA, Zhang Y, Samson S, Baas C, Kok M, Esserman LJ, van 't Veer LJ, Rugo HS, Curtis C, Klefström J, Matloubian M, Goga A. Lee JV, et al. Among authors: klefstrom j. Nat Commun. 2022 Nov 21;13(1):7140. doi: 10.1038/s41467-022-34570-5. Nat Commun. 2022. PMID: 36414627 Free PMC article. No abstract available.
Laminin matrix adhesion regulates basal mammary epithelial cell identity.
Englund JI, Bui H, Dinç DD, Paavolainen O, McKenna T, Laitinen S, Munne P, Klefström J, Peuhu E, Katajisto P. Englund JI, et al. Among authors: klefstrom j. J Cell Sci. 2022 Dec 1;135(23):jcs260232. doi: 10.1242/jcs.260232. Epub 2022 Dec 5. J Cell Sci. 2022. PMID: 36468336
64 results