Heuberger J - Search Results

1

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.

Wizenty J, Müllerke S, Kolesnichenko M, Heuberger J, Lin M, Fischer AS, Mollenkopf HJ, Berger H, Tacke F, Sigal M. Wizenty J, et al. Among authors: heuberger j. EMBO J. 2022 Jul 4;41(13):e109996. doi: 10.15252/embj.2021109996. Epub 2022 Jun 29. EMBO J. 2022. PMID: 35767364 Free PMC article.

2

Epithelial response to IFN-γ promotes SARS-CoV-2 infection.

Heuberger J, Trimpert J, Vladimirova D, Goosmann C, Lin M, Schmuck R, Mollenkopf HJ, Brinkmann V, Tacke F, Osterrieder N, Sigal M. Heuberger J, et al. EMBO Mol Med. 2021 Apr 9;13(4):e13191. doi: 10.15252/emmm.202013191. Epub 2021 Mar 3. EMBO Mol Med. 2021. PMID: 33544398 Free PMC article.

3

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.

Iftekhar A, Berger H, Bouznad N, Heuberger J, Boccellato F, Dobrindt U, Hermeking H, Sigal M, Meyer TF. Iftekhar A, et al. Among authors: heuberger j. Nat Commun. 2021 Feb 12;12(1):1003. doi: 10.1038/s41467-021-21162-y. Nat Commun. 2021. PMID: 33579932 Free PMC article.

4

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.

Heuberger J, Grinat J, Kosel F, Liu L, Kunz S, Vidal RO, Keil M, Haybaeck J, Robine S, Louvard D, Regenbrecht C, Sporbert A, Sauer S, von Eyss B, Sigal M, Birchmeier W. Heuberger J, et al. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2019699118. doi: 10.1073/pnas.2019699118. Proc Natl Acad Sci U S A. 2021. PMID: 34039707 Free PMC article.

5

NF-κB determines Paneth versus goblet cell fate decision in the small intestine.

Brischetto C, Krieger K, Klotz C, Krahn I, Kunz S, Kolesnichenko M, Mucka P, Heuberger J, Scheidereit C, Schmidt-Ullrich R. Brischetto C, et al. Among authors: heuberger j. Development. 2021 Nov 1;148(21):dev199683. doi: 10.1242/dev.199683. Epub 2021 Nov 9. Development. 2021. PMID: 34751748 Free PMC article.

6

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.

Grinat J, Kosel F, Goveas N, Kranz A, Alexopoulou D, Rajewsky K, Sigal M, Stewart AF, Heuberger J. Grinat J, et al. Among authors: heuberger j. Life Sci Alliance. 2022 Jan 21;5(4):e202101187. doi: 10.26508/lsa.202101187. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35064075 Free PMC article.

7

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation.

Kapalczynska M, Lin M, Maertzdorf J, Heuberger J, Muellerke S, Zuo X, Vidal R, Shureiqi I, Fischer AS, Sauer S, Berger H, Kidess E, Mollenkopf HJ, Tacke F, Meyer TF, Sigal M. Kapalczynska M, et al. Among authors: heuberger j. Nat Commun. 2022 Mar 24;13(1):1577. doi: 10.1038/s41467-022-29176-w. Nat Commun. 2022. PMID: 35332152 Free PMC article.

8

R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.

Fischer AS, Müllerke S, Arnold A, Heuberger J, Berger H, Lin M, Mollenkopf HJ, Wizenty J, Horst D, Tacke F, Sigal M. Fischer AS, et al. Among authors: heuberger j. J Clin Invest. 2022 Nov 1;132(21):e151363. doi: 10.1172/JCI151363. J Clin Invest. 2022. PMID: 36099044 Free PMC article.

9

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.

Lin M, Hartl K, Heuberger J, Beccaceci G, Berger H, Li H, Liu L, Müllerke S, Conrad T, Heymann F, Woehler A, Tacke F, Rajewsky N, Sigal M. Lin M, et al. Among authors: heuberger j. Nat Commun. 2023 May 25;14(1):3025. doi: 10.1038/s41467-023-38780-3. Nat Commun. 2023. PMID: 37230989 Free PMC article.

10

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness.

Grinat J, Heuberger J, Vidal RO, Goveas N, Kosel F, Berenguer-Llergo A, Kranz A, Wulf-Goldenberg A, Behrens D, Melcher B, Sauer S, Vieth M, Batlle E, Stewart AF, Birchmeier W. Grinat J, et al. Among authors: heuberger j. Nat Commun. 2020 Dec 21;11(1):6422. doi: 10.1038/s41467-020-20222-z. Nat Commun. 2020. PMID: 33349639 Free PMC article.

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