Hope KJ - Search Results

1

The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors.

Liu L, Vujovic A, Deshpande NP, Sathe S, Anande G, Chen HTT, Xu J, Minden MD, Yeo GW, Unnikrishnan A, Hope KJ, Lu Y. Liu L, et al. Among authors: hope kj. Nat Commun. 2022 Jul 4;13(1):3833. doi: 10.1038/s41467-022-31155-0. Nat Commun. 2022. PMID: 35781533 Free PMC article.

2

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity.

Hope KJ, Jin L, Dick JE. Hope KJ, et al. Nat Immunol. 2004 Jul;5(7):738-43. doi: 10.1038/ni1080. Epub 2004 May 30. Nat Immunol. 2004. PMID: 15170211 Free article.

3

Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid leukemia cells.

Chen P, Wang J, Hope K, Jin L, Dick J, Cameron R, Brandwein J, Minden M, Reilly RM. Chen P, et al. J Nucl Med. 2006 May;47(5):827-36. J Nucl Med. 2006. PMID: 16644753 Free article.

4

Targeting of CD44 eradicates human acute myeloid leukemic stem cells.

Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Jin L, et al. Among authors: hope kj. Nat Med. 2006 Oct;12(10):1167-74. doi: 10.1038/nm1483. Epub 2006 Sep 24. Nat Med. 2006. PMID: 16998484

5

Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.

Rentas S, Holzapfel N, Belew MS, Pratt G, Voisin V, Wilhelm BT, Bader GD, Yeo GW, Hope KJ. Rentas S, et al. Among authors: hope kj. Nature. 2016 Apr 28;532(7600):508-511. doi: 10.1038/nature17665. Nature. 2016. PMID: 27121842 Free PMC article.

6

Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance.

Ly M, Rentas S, Vujovic A, Wong N, Moreira S, Xu J, Holzapfel N, Bhatia S, Tran D, Minden MD, Draper JS, Hope KJ. Ly M, et al. Among authors: hope kj. Cancer Res. 2019 Nov 15;79(22):5799-5811. doi: 10.1158/0008-5472.CAN-19-0274. Epub 2019 Sep 13. Cancer Res. 2019. PMID: 31519687

7

Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis.

Salim SK, Xu J, Wong N, Venugopal C, Hope KJ, Singh SK. Salim SK, et al. Among authors: hope kj. STAR Protoc. 2020 Oct 7;1(3):100124. doi: 10.1016/j.xpro.2020.100124. eCollection 2020 Dec 18. STAR Protoc. 2020. PMID: 33377018 Free PMC article.

8

Very long chain fatty acid metabolism is required in acute myeloid leukemia.

Tcheng M, Roma A, Ahmed N, Smith RW, Jayanth P, Minden MD, Schimmer AD, Hess DA, Hope K, Rea KA, Akhtar TA, Bohrnsen E, D'Alessandro A, Mohsen AW, Vockley J, Spagnuolo PA. Tcheng M, et al. Blood. 2021 Jun 24;137(25):3518-3532. doi: 10.1182/blood.2020008551. Blood. 2021. PMID: 33720355 Free PMC article.

9

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis.

Chan DCH, Xu J, Vujovic A, Wong N, Gordon V, de Rooij LPMH, Moreira S, Joyce CE, La Rose J, Sandí MJ, Doble BW, Novina CD, Rottapel RK, Hope KJ. Chan DCH, et al. Among authors: hope kj. Blood Adv. 2021 Aug 24;5(16):3120-3133. doi: 10.1182/bloodadvances.2020002539. Blood Adv. 2021. PMID: 34406376 Free PMC article.

10

PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.

Keyvani Chahi A, Belew MS, Xu J, Chen HTT, Rentas S, Voisin V, Krivdova G, Lechman E, Marhon SA, De Carvalho DD, Dick JE, Bader GD, Hope KJ. Keyvani Chahi A, et al. Among authors: hope kj. Blood. 2022 Sep 1;140(9):992-1008. doi: 10.1182/blood.2021014698. Blood. 2022. PMID: 35639948 Free PMC article.

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