Lee AS - Search Results

1

Hydra-Elastin-like Polypeptides Increase Rapamycin Potency When Targeting Cell Surface GRP78.

Avila H, Yu J, Boddu G, Phan A, Truong A, Peddi S, Guo H, Lee SJ, Alba M, Canfield E, Yamamoto V, Paton JC, Paton AW, Lee AS, MacKay JA. Avila H, et al. Among authors: lee sj, lee as. Biomacromolecules. 2022 Aug 8;23(8):3116-3129. doi: 10.1021/acs.biomac.2c00048. Epub 2022 Jul 5. Biomacromolecules. 2022. PMID: 35786858 Free PMC article.

2

Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells.

van Lidth de Jeude JF, Meijer BJ, Wielenga MCB, Spaan CN, Baan B, Rosekrans SL, Meisner S, Shen YH, Lee AS, Paton JC, Paton AW, Muncan V, van den Brink GR, Heijmans J. van Lidth de Jeude JF, et al. Among authors: lee as. Oncogene. 2017 Jun 15;36(24):3397-3405. doi: 10.1038/onc.2016.326. Epub 2016 Nov 7. Oncogene. 2017. PMID: 27819675 Free PMC article.

3

The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer.

Samanta S, Yang S, Debnath B, Xue D, Kuang Y, Ramkumar K, Lee AS, Ljungman M, Neamati N. Samanta S, et al. Among authors: lee as. Cancer Res. 2021 Apr 1;81(7):1883-1895. doi: 10.1158/0008-5472.CAN-20-1540. Epub 2021 Feb 2. Cancer Res. 2021. PMID: 33531374 Free PMC article.

4

Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations.

Ha DP, Huang B, Wang H, Rangel DF, Van Krieken R, Liu Z, Samanta S, Neamati N, Lee AS. Ha DP, et al. Among authors: lee as. Neoplasia. 2022 Nov;33:100837. doi: 10.1016/j.neo.2022.100837. Epub 2022 Sep 24. Neoplasia. 2022. PMID: 36162331 Free PMC article.

5

Suppression of head and neck cancer cell survival and cisplatin resistance by GRP78 small molecule inhibitor YUM70.

Yamamoto V, Wang B, Lee AS. Yamamoto V, et al. Among authors: lee as. Front Oncol. 2023 Jan 11;12:1044699. doi: 10.3389/fonc.2022.1044699. eCollection 2022. Front Oncol. 2023. PMID: 36713577 Free PMC article.

6

GRP78 inhibitor YUM70 upregulates 4E-BP1 and suppresses c-MYC expression and viability of oncogenic c-MYC tumors.

Yamamoto V, Ha DP, Liu Z, Huang M, Samanta S, Neamati N, Lee AS. Yamamoto V, et al. Among authors: lee as. Neoplasia. 2024 Sep;55:101020. doi: 10.1016/j.neo.2024.101020. Epub 2024 Jul 10. Neoplasia. 2024. PMID: 38991376 Free PMC article.

7

Endoplasmic reticulum stress-inducible protein GRP94 is associated with an Mg2+-dependent serine kinase activity modulated by Ca2+ and GRP78/BiP.

Ramakrishnan M, Schönthal AH, Lee AS. Ramakrishnan M, et al. Among authors: lee as. J Cell Physiol. 1997 Feb;170(2):115-29. doi: 10.1002/(SICI)1097-4652(199702)170:2<115::AID-JCP3>3.0.CO;2-R. J Cell Physiol. 1997. PMID: 9009140

8

Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.

Zhang Y, Liu R, Ni M, Gill P, Lee AS. Zhang Y, et al. Among authors: lee as. J Biol Chem. 2010 May 14;285(20):15065-15075. doi: 10.1074/jbc.M109.087445. Epub 2010 Mar 5. J Biol Chem. 2010. PMID: 20208072 Free PMC article.

9

The critical role of GRP78 in physiologic and pathologic stress.

Pfaffenbach KT, Lee AS. Pfaffenbach KT, et al. Among authors: lee as. Curr Opin Cell Biol. 2011 Apr;23(2):150-6. doi: 10.1016/j.ceb.2010.09.007. Epub 2010 Oct 21. Curr Opin Cell Biol. 2011. PMID: 20970977 Free PMC article.

10

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting.

Ni M, Zhang Y, Lee AS. Ni M, et al. Among authors: lee as. Biochem J. 2011 Mar 1;434(2):181-8. doi: 10.1042/BJ20101569. Biochem J. 2011. PMID: 21309747 Free PMC article. Review.

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