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Integrated High-Throughput Screening and Large-Scale Isobolographic Analysis to Accelerate the Discovery of Radiosensitizers With Greater Selectivity for Cancer Cells.
Verrelle P, Gestraud P, Poyer F, Soria A, Tessier S, Lescure A, Anthony E, Corbé M, Heinrich S, Beauvineau C, Chaput L, Granzhan A, Piguel S, Perez F, Teulade-Fichou MP, Megnin-Chanet F, Del Nery E. Verrelle P, et al. Among authors: lescure a. Int J Radiat Oncol Biol Phys. 2024 Apr 1;118(5):1294-1307. doi: 10.1016/j.ijrobp.2023.09.044. Epub 2023 Sep 29. Int J Radiat Oncol Biol Phys. 2024. PMID: 37778425
Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making.
Thouvenot P, Ben Yamin B, Fourrière L, Lescure A, Boudier T, Del Nery E, Chauchereau A, Goldgar DE, Houdayer C, Stoppa-Lyonnet D, Nicolas A, Millot GA. Thouvenot P, et al. Among authors: lescure a. PLoS Genet. 2016 Jun 6;12(6):e1006096. doi: 10.1371/journal.pgen.1006096. eCollection 2016 Jun. PLoS Genet. 2016. PMID: 27272900 Free PMC article.
A siRNA screen identifies RAD21, EIF3H, CHRAC1 and TANC2 as driver genes within the 8q23, 8q24.3 and 17q23 amplicons in breast cancer with effects on cell growth, survival and transformation.
Mahmood SF, Gruel N, Chapeaublanc E, Lescure A, Jones T, Reyal F, Vincent-Salomon A, Raynal V, Pierron G, Perez F, Camonis J, Del Nery E, Delattre O, Radvanyi F, Bernard-Pierrot I. Mahmood SF, et al. Among authors: lescure a. Carcinogenesis. 2014 Mar;35(3):670-82. doi: 10.1093/carcin/bgt351. Epub 2013 Oct 22. Carcinogenesis. 2014. PMID: 24148822
High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors.
Chauvin C, Leruste A, Tauziede-Espariat A, Andrianteranagna M, Surdez D, Lescure A, Han ZY, Anthony E, Richer W, Baulande S, Bohec M, Zaidi S, Aynaud MM, Maillot L, Masliah-Planchon J, Cairo S, Roman-Roman S, Delattre O, Del Nery E, Bourdeaut F. Chauvin C, et al. Among authors: lescure a. Cell Rep. 2017 Nov 14;21(7):1737-1745. doi: 10.1016/j.celrep.2017.10.076. Cell Rep. 2017. PMID: 29141209 Free article.
Targeting CCR5 trafficking to inhibit HIV-1 infection.
Boncompain G, Herit F, Tessier S, Lescure A, Del Nery E, Gestraud P, Staropoli I, Fukata Y, Fukata M, Brelot A, Niedergang F, Perez F. Boncompain G, et al. Among authors: lescure a. Sci Adv. 2019 Oct 16;5(10):eaax0821. doi: 10.1126/sciadv.aax0821. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31663020 Free PMC article.
Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling.
Garcia-Cattaneo A, Gobert FX, Müller M, Toscano F, Flores M, Lescure A, Del Nery E, Benaroch P. Garcia-Cattaneo A, et al. Among authors: lescure a. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9053-8. doi: 10.1073/pnas.1115091109. Epub 2012 May 18. Proc Natl Acad Sci U S A. 2012. PMID: 22611194 Free PMC article.
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