Hobbs AJ - Search Results

1

The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications.

Zarenkiewicz J, Perez-Ternero C, Kojasoy V, McGinity C, Khodade VS, Lin J, Tantillo DJ, Toscano JP, Hobbs AJ, Fukuto JM. Zarenkiewicz J, et al. Among authors: hobbs aj. Free Radic Biol Med. 2022 Aug 1;188:459-467. doi: 10.1016/j.freeradbiomed.2022.06.245. Epub 2022 Jul 6. Free Radic Biol Med. 2022. PMID: 35809768 Free article.

2

Biological activity of designed photolabile metal nitrosyls: light-dependent activation of soluble guanylate cyclase and vasorelaxant properties in rat aorta.

Madhani M, Patra AK, Miller TW, Eroy-Reveles AA, Hobbs AJ, Fukuto JM, Mascharak PK. Madhani M, et al. Among authors: hobbs aj. J Med Chem. 2006 Dec 14;49(25):7325-30. doi: 10.1021/jm0604629. J Med Chem. 2006. PMID: 17149862

3

The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO.

Paolocci N, Jackson MI, Lopez BE, Miranda K, Tocchetti CG, Wink DA, Hobbs AJ, Fukuto JM. Paolocci N, et al. Among authors: hobbs aj. Pharmacol Ther. 2007 Feb;113(2):442-58. doi: 10.1016/j.pharmthera.2006.11.002. Epub 2006 Nov 29. Pharmacol Ther. 2007. PMID: 17222913 Free PMC article. Review.

4

The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols.

Miller TW, Cherney MM, Lee AJ, Francoleon NE, Farmer PJ, King SB, Hobbs AJ, Miranda KM, Burstyn JN, Fukuto JM. Miller TW, et al. Among authors: hobbs aj. J Biol Chem. 2009 Aug 14;284(33):21788-21796. doi: 10.1074/jbc.M109.014282. Epub 2009 Jun 15. J Biol Chem. 2009. PMID: 19531488 Free PMC article.

5

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility.

Ono K, Akaike T, Sawa T, Kumagai Y, Wink DA, Tantillo DJ, Hobbs AJ, Nagy P, Xian M, Lin J, Fukuto JM. Ono K, et al. Among authors: hobbs aj. Free Radic Biol Med. 2014 Dec;77:82-94. doi: 10.1016/j.freeradbiomed.2014.09.007. Epub 2014 Sep 16. Free Radic Biol Med. 2014. PMID: 25229186 Free PMC article. Review.

6

Biological hydropersulfides and related polysulfides - a new concept and perspective in redox biology.

Fukuto JM, Ignarro LJ, Nagy P, Wink DA, Kevil CG, Feelisch M, Cortese-Krott MM, Bianco CL, Kumagai Y, Hobbs AJ, Lin J, Ida T, Akaike T. Fukuto JM, et al. Among authors: hobbs aj. FEBS Lett. 2018 Jun;592(12):2140-2152. doi: 10.1002/1873-3468.13090. Epub 2018 May 24. FEBS Lett. 2018. PMID: 29754415 Free PMC article. Review.

7

A comparison of the chemical biology of hydropersulfides (RSSH) with other protective biological antioxidants and nucleophiles.

Fukuto JM, Hobbs AJ. Fukuto JM, et al. Among authors: hobbs aj. Nitric Oxide. 2021 Feb 1;107:46-57. doi: 10.1016/j.niox.2020.11.004. Epub 2020 Nov 28. Nitric Oxide. 2021. PMID: 33253886 Review.

8

Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO).

Fukuto JM, Perez-Ternero C, Zarenkiewicz J, Lin J, Hobbs AJ, Toscano JP. Fukuto JM, et al. Among authors: hobbs aj. Antioxidants (Basel). 2022 Jan 16;11(1):169. doi: 10.3390/antiox11010169. Antioxidants (Basel). 2022. PMID: 35052673 Free PMC article. Review.

9

Cardiomyocyte-derived C-type natriuretic peptide diminishes myocardial ischaemic injury by promoting revascularisation and limiting fibrotic burden.

Lowe VJ, Aubdool AA, Moyes AJ, Dignam JP, Perez-Ternero C, Baliga RS, Smart N, Hobbs AJ. Lowe VJ, et al. Among authors: hobbs aj. Pharmacol Res. 2024 Nov;209:107447. doi: 10.1016/j.phrs.2024.107447. Epub 2024 Oct 5. Pharmacol Res. 2024. PMID: 39374886 Free article.

10

Inhibition of nitric oxide synthase as a potential therapeutic target.

Hobbs AJ, Higgs A, Moncada S. Hobbs AJ, et al. Annu Rev Pharmacol Toxicol. 1999;39:191-220. doi: 10.1146/annurev.pharmtox.39.1.191. Annu Rev Pharmacol Toxicol. 1999. PMID: 10331082 Review.

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