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The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastián A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, Clark RJ, Fry BG, King GF, Ramm GA, Alewood PF, Lewis RJ, Mulvenna JP, Boyle GM, Sanchez LE, Neely GG, Miles JJ, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: miles jj. Br J Pharmacol. 2022 Oct;179(20):4878-4896. doi: 10.1111/bph.15923. Epub 2022 Jul 29. Br J Pharmacol. 2022. PMID: 35818835 Free article.
Helminth Immunomodulation in Autoimmune Disease.
Smallwood TB, Giacomin PR, Loukas A, Mulvenna JP, Clark RJ, Miles JJ. Smallwood TB, et al. Among authors: miles jj. Front Immunol. 2017 Apr 24;8:453. doi: 10.3389/fimmu.2017.00453. eCollection 2017. Front Immunol. 2017. PMID: 28484453 Free PMC article. Review.
Immune drug discovery from venoms.
Jimenez R, Ikonomopoulou MP, Lopez JA, Miles JJ. Jimenez R, et al. Among authors: miles jj. Toxicon. 2018 Jan;141:18-24. doi: 10.1016/j.toxicon.2017.11.006. Epub 2017 Nov 21. Toxicon. 2018. PMID: 29170055 Review.
Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis).
Goldenberg J, Cipriani V, Jackson TNW, Arbuckle K, Debono J, Dashevsky D, Panagides N, Ikonomopoulou MP, Koludarov I, Li B, Santana RC, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles JJ, Ge L, Kwok HF, Fry BG. Goldenberg J, et al. Among authors: miles jj. Comp Biochem Physiol C Toxicol Pharmacol. 2018 Feb;205:53-61. doi: 10.1016/j.cbpc.2018.01.001. Epub 2018 Jan 17. Comp Biochem Physiol C Toxicol Pharmacol. 2018. PMID: 29353015 Free article.
Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.
Fernandez-Rojo MA, Deplazes E, Pineda SS, Brust A, Marth T, Wilhelm P, Martel N, Ramm GA, Mancera RL, Alewood PF, Woods GM, Belov K, Miles JJ, King GF, Ikonomopoulou MP. Fernandez-Rojo MA, et al. Among authors: miles jj. Cell Death Discov. 2018 Feb 14;4:19. doi: 10.1038/s41420-018-0030-0. eCollection 2018 Dec. Cell Death Discov. 2018. PMID: 29531816 Free PMC article.
ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations.
Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: miles jj. Toxins (Basel). 2021 Feb 14;13(2):146. doi: 10.3390/toxins13020146. Toxins (Basel). 2021. PMID: 33672955 Free PMC article.
Immunological Responses to Envenomation.
Ryan RYM, Seymour J, Loukas A, Lopez JA, Ikonomopoulou MP, Miles JJ. Ryan RYM, et al. Among authors: miles jj. Front Immunol. 2021 May 10;12:661082. doi: 10.3389/fimmu.2021.661082. eCollection 2021. Front Immunol. 2021. PMID: 34040609 Free PMC article. Review.
170 results