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Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains.
Buracco S, Döring H, Engelbart S, Singh SP, Paschke P, Whitelaw J, Thomason PA, Paul NR, Tweedy L, Lilla S, McGarry L, Corbyn R, Claydon S, Mietkowska M, Machesky LM, Rottner K, Insall RH. Buracco S, et al. Among authors: claydon s. Curr Biol. 2024 Oct 7;34(19):4436-4451.e9. doi: 10.1016/j.cub.2024.08.013. Epub 2024 Sep 26. Curr Biol. 2024. PMID: 39332399 Free article.
Control of actin dynamics during cell motility.
Buracco S, Claydon S, Insall R. Buracco S, et al. Among authors: claydon s. F1000Res. 2019 Nov 25;8:F1000 Faculty Rev-1977. doi: 10.12688/f1000research.18669.1. eCollection 2019. F1000Res. 2019. PMID: 31824651 Free PMC article. Review.
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents.
Francis S, Croft D, Schüttelkopf AW, Parry C, Pugliese A, Cameron K, Claydon S, Drysdale M, Gardner C, Gohlke A, Goodwin G, Gray CH, Konczal J, McDonald L, Mezna M, Pannifer A, Paul NR, Machesky L, McKinnon H, Bower J. Francis S, et al. Among authors: claydon s. Bioorg Med Chem Lett. 2019 Apr 15;29(8):1023-1029. doi: 10.1016/j.bmcl.2019.01.035. Epub 2019 Jan 30. Bioorg Med Chem Lett. 2019. PMID: 30773430 Free PMC article.
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