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Hepatic patatin-like phospholipase domain-containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans.
Ericson E, Bergenholm L, Andréasson AC, Dix CI, Knöchel J, Hansson SF, Lee R, Schumi J, Antonsson M, Fjellström O, Nasr P, Liljeblad M, Carlsson B, Kechagias S, Lindén D, Ekstedt M. Ericson E, et al. Among authors: fjellstrom o. Hepatol Commun. 2022 Oct;6(10):2689-2701. doi: 10.1002/hep4.2032. Epub 2022 Jul 14. Hepatol Commun. 2022. PMID: 35833455 Free PMC article.
Involvement of the metabolic sensor GPR81 in cardiovascular control.
Wallenius K, Thalén P, Björkman JA, Johannesson P, Wiseman J, Böttcher G, Fjellström O, Oakes ND. Wallenius K, et al. Among authors: fjellstrom o. JCI Insight. 2017 Oct 5;2(19):e92564. doi: 10.1172/jci.insight.92564. JCI Insight. 2017. PMID: 28978803 Free PMC article.
Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function.
Sandmark J, Tigerström A, Akerud T, Althage M, Antonsson T, Blaho S, Bodin C, Boström J, Chen Y, Dahlén A, Eriksson PO, Evertsson E, Fex T, Fjellström O, Gustafsson D, Herslöf M, Hicks R, Jarkvist E, Johansson C, Kalies I, Karlsson Svalstedt B, Kartberg F, Legnehed A, Martinsson S, Moberg A, Ridderström M, Rosengren B, Sabirsh A, Thelin A, Vinblad J, Wellner AU, Xu B, Östlund-Lindqvist AM, Knecht W. Sandmark J, et al. Among authors: fjellstrom o. J Biol Chem. 2020 Apr 10;295(15):5136-5151. doi: 10.1074/jbc.RA119.011251. Epub 2020 Mar 4. J Biol Chem. 2020. PMID: 32132173 Free PMC article.
Recombinant Apyrase (AZD3366) Against Myocardial Reperfusion Injury.
Birnbaum Y, Ye R, Chen H, Carlsson L, Whatling C, Fjellström O, Ryberg E, Ye Y. Birnbaum Y, et al. Among authors: fjellstrom o. Cardiovasc Drugs Ther. 2023 Aug;37(4):625-646. doi: 10.1007/s10557-022-07329-9. Epub 2022 Feb 22. Cardiovasc Drugs Ther. 2023. PMID: 35192075
Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design.
Fjellström O, Akkaya S, Beisel HG, Eriksson PO, Erixon K, Gustafsson D, Jurva U, Kang D, Karis D, Knecht W, Nerme V, Nilsson I, Olsson T, Redzic A, Roth R, Sandmark J, Tigerström A, Öster L. Fjellström O, et al. PLoS One. 2015 Jan 28;10(1):e0113705. doi: 10.1371/journal.pone.0113705. eCollection 2015. PLoS One. 2015. PMID: 25629509 Free PMC article.
41 results