O'Brien LE - Search Results

1

Tissue Homeostasis and Non-Homeostasis: From Cell Life Cycles to Organ States.

O'Brien LE. O'Brien LE. Annu Rev Cell Dev Biol. 2022 Oct 6;38:395-418. doi: 10.1146/annurev-cellbio-120420-114855. Epub 2022 Jul 18. Annu Rev Cell Dev Biol. 2022. PMID: 35850152 Free PMC article. Review.

2

Altered modes of stem cell division drive adaptive intestinal growth.

O'Brien LE, Soliman SS, Li X, Bilder D. O'Brien LE, et al. Cell. 2011 Oct 28;147(3):603-14. doi: 10.1016/j.cell.2011.08.048. Cell. 2011. PMID: 22036568 Free PMC article.

3

Beyond the niche: tissue-level coordination of stem cell dynamics.

O'Brien LE, Bilder D. O'Brien LE, et al. Annu Rev Cell Dev Biol. 2013;29:107-36. doi: 10.1146/annurev-cellbio-101512-122319. Epub 2013 Aug 5. Annu Rev Cell Dev Biol. 2013. PMID: 23937350 Free PMC article. Review.

4

A Model for Adult Organ Resizing Demonstrates Stem Cell Scaling through a Tunable Commitment Rate.

Du X, O'Brien LE, Riedel-Kruse IH. Du X, et al. Biophys J. 2017 Jul 11;113(1):174-184. doi: 10.1016/j.bpj.2017.05.040. Biophys J. 2017. PMID: 28700915 Free PMC article.

5

Independently paced Ca2+ oscillations in progenitor and differentiated cells in an ex vivo epithelial organ.

Kim AA, Nguyen A, Marchetti M, Du X, Montell DJ, Pruitt BL, O'Brien LE. Kim AA, et al. Among authors: o brien le. J Cell Sci. 2022 Jul 15;135(14):jcs260249. doi: 10.1242/jcs.260249. Epub 2022 Jul 19. J Cell Sci. 2022. PMID: 35722729 Free PMC article.

6

Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins.

Lipschutz JH, Guo W, O'Brien LE, Nguyen YH, Novick P, Mostov KE. Lipschutz JH, et al. Mol Biol Cell. 2000 Dec;11(12):4259-75. doi: 10.1091/mbc.11.12.4259. Mol Biol Cell. 2000. PMID: 11102522 Free PMC article.

7

Epithelial polarity and tubulogenesis in vitro.

Zegers MM, O'Brien LE, Yu W, Datta A, Mostov KE. Zegers MM, et al. Trends Cell Biol. 2003 Apr;13(4):169-76. doi: 10.1016/s0962-8924(03)00036-9. Trends Cell Biol. 2003. PMID: 12667754 Review.

8

ERK and MMPs sequentially regulate distinct stages of epithelial tubule development.

O'Brien LE, Tang K, Kats ES, Schutz-Geschwender A, Lipschutz JH, Mostov KE. O'Brien LE, et al. Dev Cell. 2004 Jul;7(1):21-32. doi: 10.1016/j.devcel.2004.06.001. Dev Cell. 2004. PMID: 15239951 Free article.

9

STAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesis.

Kim M, O'Brien LE, Kwon SH, Mostov KE. Kim M, et al. Mol Biol Cell. 2010 Nov 15;21(22):3926-33. doi: 10.1091/mbc.E10-02-0112. Epub 2010 Sep 22. Mol Biol Cell. 2010. PMID: 20861313 Free PMC article.

10

Feedback regulation of steady-state epithelial turnover and organ size.

Liang J, Balachandra S, Ngo S, O'Brien LE. Liang J, et al. Nature. 2017 Aug 31;548(7669):588-591. doi: 10.1038/nature23678. Epub 2017 Aug 23. Nature. 2017. PMID: 28847000 Free PMC article.

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